Grey’s Anatomy

Grey ’s Anatomyhas seen a hatful of character amount and go , and , as a result , some amazing friendly relationship have been struck up on the mode . WhenAlex Karevfirst appear in the pilot episode back in 2005 , the character was write in belatedly to give the show a act of an boundary , as Alex was a total jerk .

Over meter , though , Alex gradually began to mellow and became the piece everyone love he was inside . A major ingredient in Alex ’s development was Arizona Robbins , head of Pediatric surgery , who taught Alex to be a better someone and a brilliant surgeon . However ,   there are many reasons why these two are n’t really friends .

Alex Didn’t Initially Like Arizona’s Personality

When Alex and Arizona first met , Arizona was the young attendance assigned to a untried male child ’s grammatical case after the premature doctor give-up the ghost . Arizona insisted on putting the small fry on the transplant list as soon as potential , and she was surprised that nobody had done that already , given the state of the boy ’s intestines and liver .

Both Alex and Miranda Bailey did n’t care Arizona ’s new approach , and they quetch about her behind her back .   Alex was bugged by Arizona ’s perkiness , even when they had to reap a dying kid ’s electronic organ to save their own patient .

Alex Shamed Arizona

When Arizona made herGrey ’s Anatomydebut in season five , she and Callie Torres were immediately attracted to each other . After a sluggish start , they embarked on a human relationship with each other , going on to become an extremely democratic fan - favorite couple .

However , in the time of year nine finale , Arizona cuckold on Callie , who was clearly devastated and angry , refusing to forgive Arizona . Arizona planned an elaborated apology , but Alex told her to just say sorry , dishonour her . While Arizona ’s action at law were questionable , you just do n’t shame a friend like that .

Arizona Gave Alex Weed Cookies

In one of time of year 14 ’s funniest episodes , the majority of the operative staff at Grey Sloan Memorial Hospital were rendered useless after Arizona was accidentally given homemade biscuit laced with mourning band from a grateful patient . Arizona   had already handed the cooky around before she realized .

One of the recipients of the gage cookies was Alex , who started acting mellow , force Amelia Shepherd and Owen Hunt to convey him home with them . While this was a big installment , Alex ( and the other doctors ) could have gotten into serious trouble all because of Arizona ’s mistake .

Alex Slept With Callie

To be clear , neither Alex nor Callie cheated on Arizona , as this all direct place in a flashback . In time of year six , the doctors attended a series of lectures hand by attending and fourth-year members of stave , including Callie . Callie was struggle with heart , and so Alex and Arizona encouraged her from the hearing .

After a precarious start , Callie soon ground her vallecula , and her take shell was actually quite interesting . After encountering difficulty , Alex and Callie managed to spare their affected role , which led to them celebrate by sustain sex . Arizona did n’t know about this , and so she was understandably a bit cross .

Alex Beat Up Andrew DeLuca

When Alex seem in early seasons , he was a misogynistic , chesty , hot - manoeuvre shtup . Thankfully , though , he presently farm up to become a likeable and trustworthy colleague . However , things soon get awkward .

In season 13 , Arizona was then living withAndrew DeLuca , and they had built up quite a sweet friendship despite Arizona being DeLuca ’s knob . Unfortunately , due to a fatal mistaking , Alex saw DeLuca withJo Wilsonand severely thump him up . DeLuca had to undergo multiple surgical process , and Alex was get . It should n’t have to be said , but beat up your booster ’s flatmate is a no go where friendly relationship is have-to doe with .

Alex Left Arizona For Johns Hopkins

In season 8 , Alex and all the other 5th - year residents became involve in a mad scramble in a command to retrieve a fellowship for next year . Alex was skin slightly , as his labor where he brought children to the hospital for surgery was over a year ago . Just when he was about to give up , he get an offer from Johns Hopkins .

They were improbably impressed by his performance at his board exams and made him a once in a lifetime offer . of course , Alex considered all his options before choosing to admit the offer . However , this meant give away Arizona who had taught him everything he know and who was expecting him to appease with her .

Alex Refused To Testify On Arizona’s Behalf

Arizona and Callie ’s family relationship was great while it lasted , but , sadly , in season 11 , the two surgeons went their disjoined ways . Fortunately , they still stay on civil towards each other and even considered them to be friends . However , when Callie announced she was prompt to New York , that all went out the windowpane .

Callie assumed she would be taking Sofia with her , much to Arizona ’s repugnance . The couplet then initiated a savage detention battle that did n’t incisively paint either woman in a good luminance . However , Arizona ask her friends to guarantee for her , and , when she postulate Alex , he refused , state he could n’t pick out sides .

Alex Was The Reason Why Arizona Was In The Plane Crash

When Arizona ascertain out that Alex was leaving her for Johns Hopkins , it ’s good to say that she was not at all glad . In all fairness to Alex , Arizona ’s speculative mood was not only due to his perceived treason ; earlier that day , Arizona ’s late buddy ’s childhood friend told her that he was dying .

Unable to deal with the fact that she would soon lose another part of her brother , Arizona was already on sharpness . When Alex told her about his decision , she tear and took his position on the plane , as well as removing Alex from all pediatric operation . If it were n’t for Alex , Arizona would still have her leg .

Alex Cut Off Arizona’s Leg

For the most part , watching Arizona ’s and Alex ’s friendship blossom over the course of ten seasons was a joy to lay eyes on . Alex con how to be sore , not just with his young patients , but their parents , as well , and Arizona get a bright new peds surgeon .

This all went smoothly until the dreaded plane crash occurred . If anything , the aftermath was even more beastly than the crash itself . The spite were transferred to Seattle Grace , but Arizona ’s infection in her stage threaten to pop her . Therefore Alex had to burn off her ramification , potentially jeopardizing their friendship .

Arizona Is Alex’s Mentor

Alex and Arizona did have an amazing relationship onGrey ’s Anatomy , despite all their ups and downs . However , the main reason why they are not truly Friend is because their kinship consist of a wise man / mentee post .

They ’ve never really hung out together out of doors of work in good order , and they do n’t really discourse their personal lives with each other . They like each other and respect the hell out of each other , but it ’s principally professional between the two . Despite this , both Arizona and Alex have had a monumental impact on each other ’s lives , and they will always be crucial to one another .

NEXT : Grey ’s Anatomy : 5 Characters Who Have Grown A Lot ( & 5 Who Have n’t )

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Robbins looking down and smiling in Greys Anatomy

An image of Alex Karev wearing his blue scrubs in Grey’s Anatomy

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Callie And Arizona At Airport In Grey’s Anatomy

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Alex before getting arrested

Alex And Arizona in Greys Anatomy

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