Grey’s Anatomy
The first episodes of ABCGrey ’s Anatomyaired on March 27 , 2005 , and there have been 375 episodes ever since . A mint of actor have make out and move over the year , which is understandable . A high-pitched overturn is expected for such a lengthy show . Actors unremarkably sense the desire to take on different projects while new characters make previous ones irrelevant .
A few public figure that were there at the very beginning are still appearing on the show with no intention to leave . These include Ellen Pompeo , Justin Chambers , Chandra Wilson , and James Pickens Jr. Others exit and became successful elsewhere while others somehow fell off the Hollywood microwave radar .
Sandra Oh
Sandra Oh portrayed Cristina Yang for the first 10 seasons . At the time she was leaving the show , her character had develop from a surgical intern to the Director of Cardiothoracic Surgery at the Klausman Institute for Medical Research .
Oh has had a outstanding run outside the show . She currently has a principal role in the undercover agent dramaKilling Evewhere she portray a British intelligence agent . In addition to that , Oh set raw records as the first actress of Asiatic descent to get an " Outstanding Lead Actress in a Drama Series " Emmy nominating address and as the first Asiatic actress to gain two Golden Globes .
Katherine Heigl
Heigl starred as surgical oncologist Izzie Stevens for the first 6 seasons of the medical play . The role won her an Emmy for " Outstanding Supporting Actress in a Drama Series . " She latterly deliver to the show courtesy of a guest appearance in Season 16 ’s " Leave a Light On . "
After her passing , Heigl starred in a number of romcoms . She then break on to have a main role in the sound dramaSuitswhere she play unexampled law firm partner Samantha Wheeler . She also has a starring role in the new Netflix seriesFirefly Lane . Apart from that , she is set to portray the first female candidate for the presidential term of the United States in the limited seriesWoodhull .
T. R. Knight
Knight was the harm surgeon George O’Malley until Season 5 . The role player gave a yoke of reasons for go away the show that included failure to concord with showrunner Rhimes and his character ’s lack of ample screen door - time .
Life has n’t been bad for Knight away fromGrey ’s Anatomy . He presently has a main function in the critically acclaimed seriesThe Flight Attendant . In it , he play the judgmental elder brother of Cassie , a flying attendant impersonate by formerThe Big Bang Theorystar Kaley Cuoco . As a extremity of the LGBTQ+ community , Knight is a striking militant too .
Isaiah Washington
Washington ’s character Preston Burke will always be remember as the Isle of Man wholeft Cristina at the communion table . Even though the cardiothoracic sawbones redeemed himself , it ’s inconceivable to forget the incident . Washington go forth the show after the third time of year .
The actor has had a twosome of key function after leavingGrey ’s Anatomy . His most celebrated one is that of Chancellor Jaha in the post - revelatory dramaThe 100 . More recently , he has been Mayor Tydell Ruffin in the Starz seriesP - Valley . Washington also hosts a travel and cooking show titledIsaiah Washington : Kitchen Talkon Fox Nation .
Patrick Dempsey
Dempsey ’s eccentric Derek Shepherd aka McDreamy had " Gifted Hands . " He was the only doctor who would lief take on the most hard of vitrine . His romance with Meredithwas also something to lay eyes on . In Season 17 , he appeared in Meredith ’s visions after she was diagnose with Covid-19 .
Except for the financial thriller seriesDevils , Dempsey has n’t been a part of any major productions of late . However , he is actively participate in several other fields , including belt along . He is the possessor of the Dempsey Racing Team . The role player also does advertising work for make such as L’Oreal and Versace .
Kate Burton
Burton is best think back for play Meredith ’s female parent and world - notable surgeon Ellis Grey . She appear on the show for the first three season then left onceher character succumbed to Alzheimer ’s .
The actress appear in the other popular Shondaland showScandalwhere she portrayedVice President Sally Langston . The character clear her an Emmy nomination . More recently , she had a guest persona in the FOX proceduralProdigal Son .
Kate Walsh
For the first eight seasons , Walsh had a repeat persona as Addison Montgomery , the duple add-in - certified OB / GYN , who specialise in fetal operation . She also portrayed the same role in the spinoffPrivate Practice .
After will the show , Walsh went on to star in the Netflix hit series13 Reasons Why , as the parent of a child who pull self-destruction . At the second , she also has a recurring role as antagonist " The Handler " in another Netflix attain serial publication , The Umbrella Academy . And the Netflix glory does n’t terminate there . She is in the Netflix OriginalEmily in Paris , too .
Sarah Utterback
Sarah Utterback played Olivia Harper , a nursemaid at Seattle Grace whohad an matter with both Alex and George . She was give the sack after it was announced that Seattle Grace was unify with Mercy West Medical Center . Utterback returned in Season 14 ’s " Bad Reputation " in a Edgar Guest electrical capacity .
The actress has n’t done much after leavingGrey ’s Anatomy . Her last credited role ( apart from her Season 14 return ) was in the dead - inhabit 2012 comedyReception . Hopefully , fans will get to see her in something raw soon .
Eric Dane
Dane is best remembered for portraying the medical drama ’s resident man-about-town Mark Sloan aka McSteamy . Sadly , the rooter - favourite lineament succumbed to injuries he support during the notorious plane crash .
At the moment , Dane has a main role in the HBO stripling dramaEuphoriawhere he toy a rigid father who happens to be a treble biography . Prior to that , he star in the military dramaThe Last Shipas Capt . Tom Chandler .
Steven W. Bailey
Bailey was one of the thespian who got to portray two different fiber inGrey ’s Anatomy . First , he appeared as the anesthesiologist Jeremy in Season 1 before returning in Season 2 as Joe , the owner ofEmerald City Bar aka Joe ’s . The actor give the show after Season 7 , though the bar stay to operate .
The player has mostly land guest use in late eld , appearing in serial publication such asYouandShameless . He has also appear in legion commercials over the years .
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