Grey’s Anatomy
ABC’sGrey ’s Anatomyis among thelongest - running game appearance of all clock time . For years , it has prevent the world harbour . There has been romance , drama , and some very stimulating legal action sequences . Another reason why the viewers keep coming back is because of the talented and charismatic mold . Without them , the show would n’t have lasted as long as it has .
However , sometimes sports fan have had to say good day to sure buff - pet fibre as several actor have decided to pursue other part . While many fans were let down with some going , they did find it interesting how their last lines reflected their shock on the show . particularly when you compare it to their first .
Izzie Stevens
“ Maybe it ’s professional jealousy . Maybe she ’s brilliant and they call her Nazi because they ’re envious . ” – “ No you ’re not , you ’re just a bunch of mass I worked with , and I can find that anywhere . ”
Katherine Heigl ’s Izzie Stevens starts out as an intern at Seattle Grace Hospital , just like Meredith Grey . In her first ancestry , she was search the rationale over Dr. Miranda Bailey ’s nickname . Overall , Heigl received praised for her portrayal of the character , although there wereinstances when Izzie stepped out of line of descent and refused to espouse hospital protocol . Heigl famously adjudicate to leave the show after require the Emmy ’s to revoke her nomination . Her last line , which is in response to Meredith convincing her to stay , seems to echo Heigl ’s existent sentiment towards the show at that time .
Preston Burke
“ We Have A Wet Fish On Dry Land . ” - “ Do you ? ”
Isaiah Washington ’s Preston Burke was introduced to us at the start of the time of year and his first line references the input he made upon being present a patient ’s compositor’s case during the pilot . At some point , Preston fall for Meredith ’s best friend , houseman Cristina Yang .
Their story may have progressed differently had Washington not been enkindle from the show followingallegations of using a homophobic aspersion against his co - star , T.R. Knight . Despite his firing , Washington reprised his role for an episode in season 10 . In his last crease , Preston asks Cristina if she want to manage his enquiry hospital in Switzerland . The fact that his last line is just two word shows that Burke was no longer had an impact on the show .
George O’Malley
“ You got the Nazi ? So did I. At least we ’ll be tortured together . ” – “ That ’s how I reckon it would start . ”
Knight ’s deliver his first line to Meredith as they were about to start their first shift as interns under Dr. Bailey . specially during the show ’s earlier seasons , it became clear that George had a serious crush on Meredith . Unfortunately , she did n’t revert his warmheartedness .
During the season 5 finale , George bring out he unite the Army . In his last line , he responds to Bailey ’s shock upon learning the word . If fans take a closer expression at his first and last lines , one can see the onward motion of their relationship . Where he was ab initio fearful of Bailey , he ended up building a stiff adhesion with her . unluckily , their friendly relationship was cut short whenGeorge was killed off in a heartbreaking manner .
Callie Torres
“ George O’Malley ? ” – “ Thank you . ”
When she was insert to the show , Callie was looking for George because she had to treat him after the interne dislocate his shoulder joint . This is why her first - ever line involves demand for him . In 2016 , it was announce that thespian , Sara Ramirez , who portrays Callie , was leaving the show .
According toThe Hollywood Reporter , the show ’s creator , Shonda Rhimes , issued a statement saying , “ I will miss Callie enormously , but am excited for what the futurity hold for Sara . ” In her last line , Callie thanks Arizona after she allows her to move to New York and share custody of their daughter . Considering she had been a master persona , her last words seemed a little anti - climatic .
Addison Montgomery
“ You ’d have sex if you ’d trouble oneself to suffice any one of my earpiece call . ” – “ It ’s not yours . "
Addison ’s first line involve the meter she appear before Derek and Meredith . This is also the bit when the watcher see that McDreamy is married . compare the two doctors , everyone can understand how Meredith could be threatened by Addison sinceshe ’s a double dining table - indorse OB / GYN who also specializes in neonatal operating theater .
luckily for Meredith , Addison decided to end affair and move to California . That said , Addison ’s last line happens in an episode that involves an alternate reality , one where Addison have significant and she later profess to Derek that he ’s not the beginner . It just last to show that she and Derek were never meant to be .
Lexie Grey
“ Can I bribe you a drink ? ” – “ stand for to be . "
Lexie Grey made quite an impression from the very beginning . When the viewers were first introduced to the younger Grey , she did frustratefans as it appeared she could be another love interestingness , dally with the neurosurgeon .
However , as the character evolved on the show , it became apparent that Mark Sloan was her true sexual love . Despite all their ups - and - down , everyone roll in the hay they could n’t stayaway from each other as something always quarter them back together . In her last dividing line , Lexie recognise that she and Mark were “ meant to be ” shortly before succumbing to her injuries in the carpenter’s plane crash .
Cristina Yang
“ I hear one of them is a model . severely ? Like that ’s go to help with the esteem affair . ” – “ Let ’s do it . ”
Cristina delivers her first melodic phrase as she was about to bug out her first day of internship with Meredith . Throughout her sentence on the show , she became one of the best doctor that Grey - Sloan has ever had . She was also seen to become romantically involved with Preston Burke and Owen Hunt .
After Preston left her at the altar , she extend working for the hospital long after . The two were by and by reunited in season 10 , where Cristina concord to take over Preston ’s Switzerland hospital . In her last melody , the viewers see her fain squeeze her newfound responsibility .
Mark Sloan
“ Invasive non - little - cell with a account of COPD . That ’s pretty much a goner , correct ? ” – “ 30 Day . ”
In his first line , Mark flirts with Meredith upon arriving at the hospital , something that Derek did n’t appreciate at all . finally , fans learn that Mark was the intellect that Derek and Addison ’s man and wife fell aside .
However , in the show , Mark began to dismiss his womanizing direction when he fell for Lexie . lamentably , he also died from the injuries he sustained in the plane clang . As his condition was getting bad , he sign a form that postulate the “ time the infirmary can be withdrawing his care . ” In his last line , Mark respond , “ 30 days . ” It may have been brusque but it was waste all the same as he had speedily become a fan - favorite .
Derek Shepherd
“ This is … ” – “ Love you ”
In his first melody , the viewers discover Derek in Meredith ’s house after they had a theorize one - night standstill . work at the same infirmary , though , appropriate them to keep seeing each other . And when fans learned that Derek was married to Addison , they were still hoping that Derek and Meredith would end up together in the long run .
Eventually , this materialise although their kinship faced a muckle of challenges throughout the episodes . However , when Patrick Dempsey decide to leave the show , the part got killed off . In his last wrinkle , Derek is shown on a ferry recording a voicemail for Meredith , declare his dear for the last meter . It was nice to see Derek ’s first and last line were directed towards Meredith .
Alex Karev
“ 007 . ” – “ I love you , Dr. Bailey . Dr. Alex Karev . ”
When fans first met him , Alex fare off as a cocky intern and in his first line , he emphasise this jerk - like behavior when he concern to George as “ 007 . ” In the goal , it became clear that Alex had always been in passion with Izzie . In fact , the character reference leaves to be with her and their nestling in the end . By looking at his first and last lines , it ’s quite interesting to see how much he had changed over the age .
NEXT : Grey ’s Anatomy : 10 Most Emotional Alex Karev Quotes
