Grey’s Anatomy

There are many reasons to loveGrey ’s Anatomy . The compulsively watchable show features impossibly quotable talks , epic romances and mad aesculapian pillowcase rig to an awesome soundtrack . Currently roll up its fifteenth season , the series was of late renewed for two more , so devotee wo n’t have to say goodbye any meter soon .

One of the defining characteristics ofGrey ’s Anatomyhas become its revolving cast of characters . The medico that populated Seattle Grace in the pilot are now almost completely different , with very few keystone . Even the name of the infirmary has vary . Anyone who ’s stuck with the series will state you that it has viewers regularly reaching for their hankies . Over the years , lover have pronounce goodbye to passel of beloved characters . Here are the 10 that wound the most . Side note : how does Grey Sloan Memorial continue to keep engage medico when the infirmary has such a gamy mortality rate for employees ?

Samuel Norbert Avery

spectator   triumph when April Kepner and Jackson Avery finally get together - no-account Matthew . Whenthe   lover ducky couplerealized that they were exit to have a infant , both were overjoyed . However , that agitation was shortly decimated by the world that their child ’s poor wellness would n’t see him survive outside the uterus .

Due to April ’s religious opinion , she reject to terminate the maternity , a decisiveness that she and Jackson clash over . In the end , April give way parentage to the small fry that they named Samuel Norbert Avery . His parent hold him for several agonizing here and now until he died . Jackson and April did eventually have another infant , but their relationship never recovered from the loss of Samuel .

Ellis Grey

Ellis Grey ( Kate Burton ) was never a great ma . A fantastic surgeon , sure , but she was never going to win Mother of the Year . Much of Meredith ’s “ moody and voluminous ” personality could be attributed to her upbringing . In fact , Ellis was such an unlikable character that her death on its own might not have been so heartbreaking , if not for the effect that it had on Meredith .

After Ellis was diagnose with former onset Alzheimer ’s disease , Meredith became her chief caretaker , as well as the exclusive steward of her secret . After a perturbing conversation that almost made Meredith decide to give up on life completely , female parent and daughter finally had a nice chat … in Meredith ’s subconscious mind . She eventually return to the land of the animation , but Ellis was gone for proficient .

Henry Burton

Before Scott Foley was   bashing skulls onScandal , he was stealing hearts onGrey ’s Anatomy . As Henry Burton , Foley not only charmed audiences , but Dr. Teddy Altman as well . In fact , Teddy was so taken with him that she declare oneself to get married   the   nitty-gritty patient so that he could utilize her health insurance , granting him the   medical charge that he so desperately needed . Despite the contrived way in which their marriage began , as well as Teddy ’s various attempts not to come for him , they finally became a real mates .

This isGrey’sthough , so presently after , Henry was hie into surgery . It was performed by Cristina , but the identity of the patient was designedly kept from her in the hopes that she could save him . She was abortive and Henry died , break viewers ’ hearts right along with Teddy ’s .

Adele Webber

Poor Richard Webber . To have not one , but two adult female that you love suffer from Alzheimer ’s disease , is a brutal twist of fate indeed . After watch over Ellis slip away , Richard was forced to do the same with his wife , Adele ( Loretta Divine ) . From the crushing realization that he could no longer deal for her to the revelation that she ’d fallen for someone else and no longer recognize him , her battle with the disease was brutal .

Adele eventually elapse from a heart attack . Even after her last , Richard still showed up to Bailey ’s marriage , despite his clear broken heart .   It was one of the most soul - crushing instant inGrey’shistory .

Lexie Grey

Grey ’s Anatomyis live for its brutal season finis and although season 6 wins in pure carnage , few episodes have had more long - go ramifications than the plane clank that crest time of year 8 . Lexie Grey ( Chyler Leigh ) had become a buff favorite by that point and no one saw her death come . The image of her slipping away while trapped under the wreckage as Mark holds her hand is one of the show ’s most painful scenes .

Compounding the government issue was Lexie and Mark reaffirm their love for one another - the fan favored duad had been break down up for quite some time . In typicalGrey’sfashion , the consultation acquire the reunification that they ’d been hold off for , but only so writers could further turn the knife .

Mark Sloan

address of the withering plane crash and the author ’ predilection for twisting the knife , Mark Sloan ( Eric Dane ) made it back to Seattle , but only so that he could die there . Apparently , when it was decide that Sloan was to be written out of the show , transmit him to LAto live happily ever after with Addisonover onPrivate Practicewas in short considered . However , the mind was scrap due to Mark ’s grief over Lexie ’s end , as well as the fact that he ’d never exit his girl , peculiarly in light of Arizona ’s injuries .

The most painful part of saying goodby to McSteamy was thatGrey’smade us say it twice . buff were draw to watch the excruciating setting of his friends choosing to withdraw fear - per his want . However , the very next installment featured flashbacks revealing that he was awake for a while before slue into a coma .

George O’Malley

While it is honest that the tragical decease of George O’Malley ( T.R. Knight ) would ’ve had more shock if he ’d spent a morsel more time on silver screen in time of year 5 , it was still fabulously upsetting . Of naturally , he pop off out like the hero that fans always knew he was , literally jumping in front of a bus to bring through a stranger ’s life . By the time he was step on it to the hospital , George was completely unrecognizable .

It was nice to see him share a net present moment with Izzie somewhere between life and death , rollick his Modern uniform . Still , he was one of the original interns , although hardly any of them are forget by this point . He was the first to go and it waspainful to see .

Doc

Doc was Meredith ’s dog during season 2 . He ’s the cause that she meet handsome veteran Finn Dandridge , but the canine tooth fellow traveler also became an unexpected link to Derek after Mer had to re - home him with McDreamy .

Sadly , Doc was n’t long for this world . Finn diagnosed him with bone cancer and the only tangible choice was mercy killing . Derek and Meredith were both with him in the terminal , not only sorrow Doc , but   also the love that they still feel so strongly for one another . If this death did n’t make you cry , it ’s entirely possible that you do n’t have a heart at all .

Denny Duquette Jr.

When asked about theirfavoriteGrey’spatients , almost everyone will reference Denny Duquette Jr. Jefferey Dean Morgan convey his undeniable charms to the part , once again raise the question of why every video show and movie seems determined to kill off the character that he plays . No matter how wrong viewers knew the Latinian language between Izzie and Denny was , it was impossible not to root for them .

Few moments in the series were as gut - wrench as Izzie showing up in a real promenade apparel only to discover that despite all her insane endeavour to save his life , Denny was go . As much as it hurt to watch his demise , most fans would ’ve preferred he stayed dead , rather than his strange season 5 return as a touch / delusion .

Derek Shepherd

Unequivocallythe love of Meredith Grey ’s life , there will never be another Der and Mer no matter how hardGrey ’s Anatomytries to create one . The romance between Meredith and Derek Shepherd ( Patrick Dempsey ) was one of the relationship that made the early seasons of the serial so compulsively watchable . Their will - they - or - won’t - they moral force had viewers hook from the start and introducing Derek ’s surprise spouse did footling to derail that faith .

As truly grievous as it was to watch Derek ’s last - which was basically the resultant role of medical incompetence - there really was no other way to write him out of the show and still remain true to the epic love story that Shonda Rhimes had been telling for over a decennium . McDreamy is still very much missed by both Meredith and fans .

NEXT : Grey ’s Anatomy : 13 Storylines That Hurt The Show ( And 12 That hold open It )

Grey’s Anatomy Poster

Grey’s Anatomy Plane Crash

April and Jackson holding Samuel in Grey’s Anatomy

Ellis Grey Grey’s Anatomy

Scott Foley as Henry

Loretta Devine and James Pickens Jr as Adele and Richard Webber in Grey’s Anatomy

Chyler Leigh as Dr Lexie Grey in Grey’s Anatomy

Eric Dane as Mark Sloan in grey’s anatomy

George O’Malley in uniform Grey’s Anatomy

Meredith and Finn with a dog on Grey’s Anatomy

Denny Duquette in hospital bed smiling in Grey’s Anatomy

Patrick Dempsey as Dr Derek Shepherd Greys Anatomy

Grey’s Anatomy