Grey’s Anatomy
There are many reasons to loveGrey ’s Anatomy . The compulsively watchable show features impossibly quotable talks , epic romances and mad aesculapian pillowcase rig to an awesome soundtrack . Currently roll up its fifteenth season , the series was of late renewed for two more , so devotee wo n’t have to say goodbye any meter soon .
One of the defining characteristics ofGrey ’s Anatomyhas become its revolving cast of characters . The medico that populated Seattle Grace in the pilot are now almost completely different , with very few keystone . Even the name of the infirmary has vary . Anyone who ’s stuck with the series will state you that it has viewers regularly reaching for their hankies . Over the years , lover have pronounce goodbye to passel of beloved characters . Here are the 10 that wound the most . Side note : how does Grey Sloan Memorial continue to keep engage medico when the infirmary has such a gamy mortality rate for employees ?
Samuel Norbert Avery
spectator triumph when April Kepner and Jackson Avery finally get together - no-account Matthew . Whenthe lover ducky couplerealized that they were exit to have a infant , both were overjoyed . However , that agitation was shortly decimated by the world that their child ’s poor wellness would n’t see him survive outside the uterus .
Due to April ’s religious opinion , she reject to terminate the maternity , a decisiveness that she and Jackson clash over . In the end , April give way parentage to the small fry that they named Samuel Norbert Avery . His parent hold him for several agonizing here and now until he died . Jackson and April did eventually have another infant , but their relationship never recovered from the loss of Samuel .
Ellis Grey
Ellis Grey ( Kate Burton ) was never a great ma . A fantastic surgeon , sure , but she was never going to win Mother of the Year . Much of Meredith ’s “ moody and voluminous ” personality could be attributed to her upbringing . In fact , Ellis was such an unlikable character that her death on its own might not have been so heartbreaking , if not for the effect that it had on Meredith .
After Ellis was diagnose with former onset Alzheimer ’s disease , Meredith became her chief caretaker , as well as the exclusive steward of her secret . After a perturbing conversation that almost made Meredith decide to give up on life completely , female parent and daughter finally had a nice chat … in Meredith ’s subconscious mind . She eventually return to the land of the animation , but Ellis was gone for proficient .
Henry Burton
Before Scott Foley was bashing skulls onScandal , he was stealing hearts onGrey ’s Anatomy . As Henry Burton , Foley not only charmed audiences , but Dr. Teddy Altman as well . In fact , Teddy was so taken with him that she declare oneself to get married the nitty-gritty patient so that he could utilize her health insurance , granting him the medical charge that he so desperately needed . Despite the contrived way in which their marriage began , as well as Teddy ’s various attempts not to come for him , they finally became a real mates .
This isGrey’sthough , so presently after , Henry was hie into surgery . It was performed by Cristina , but the identity of the patient was designedly kept from her in the hopes that she could save him . She was abortive and Henry died , break viewers ’ hearts right along with Teddy ’s .
Adele Webber
Poor Richard Webber . To have not one , but two adult female that you love suffer from Alzheimer ’s disease , is a brutal twist of fate indeed . After watch over Ellis slip away , Richard was forced to do the same with his wife , Adele ( Loretta Divine ) . From the crushing realization that he could no longer deal for her to the revelation that she ’d fallen for someone else and no longer recognize him , her battle with the disease was brutal .
Adele eventually elapse from a heart attack . Even after her last , Richard still showed up to Bailey ’s marriage , despite his clear broken heart . It was one of the most soul - crushing instant inGrey’shistory .
Lexie Grey
Grey ’s Anatomyis live for its brutal season finis and although season 6 wins in pure carnage , few episodes have had more long - go ramifications than the plane clank that crest time of year 8 . Lexie Grey ( Chyler Leigh ) had become a buff favorite by that point and no one saw her death come . The image of her slipping away while trapped under the wreckage as Mark holds her hand is one of the show ’s most painful scenes .
Compounding the government issue was Lexie and Mark reaffirm their love for one another - the fan favored duad had been break down up for quite some time . In typicalGrey’sfashion , the consultation acquire the reunification that they ’d been hold off for , but only so writers could further turn the knife .
Mark Sloan
address of the withering plane crash and the author ’ predilection for twisting the knife , Mark Sloan ( Eric Dane ) made it back to Seattle , but only so that he could die there . Apparently , when it was decide that Sloan was to be written out of the show , transmit him to LAto live happily ever after with Addisonover onPrivate Practicewas in short considered . However , the mind was scrap due to Mark ’s grief over Lexie ’s end , as well as the fact that he ’d never exit his girl , peculiarly in light of Arizona ’s injuries .
The most painful part of saying goodby to McSteamy was thatGrey’smade us say it twice . buff were draw to watch the excruciating setting of his friends choosing to withdraw fear - per his want . However , the very next installment featured flashbacks revealing that he was awake for a while before slue into a coma .
George O’Malley
While it is honest that the tragical decease of George O’Malley ( T.R. Knight ) would ’ve had more shock if he ’d spent a morsel more time on silver screen in time of year 5 , it was still fabulously upsetting . Of naturally , he pop off out like the hero that fans always knew he was , literally jumping in front of a bus to bring through a stranger ’s life . By the time he was step on it to the hospital , George was completely unrecognizable .
It was nice to see him share a net present moment with Izzie somewhere between life and death , rollick his Modern uniform . Still , he was one of the original interns , although hardly any of them are forget by this point . He was the first to go and it waspainful to see .
Doc
Doc was Meredith ’s dog during season 2 . He ’s the cause that she meet handsome veteran Finn Dandridge , but the canine tooth fellow traveler also became an unexpected link to Derek after Mer had to re - home him with McDreamy .
Sadly , Doc was n’t long for this world . Finn diagnosed him with bone cancer and the only tangible choice was mercy killing . Derek and Meredith were both with him in the terminal , not only sorrow Doc , but also the love that they still feel so strongly for one another . If this death did n’t make you cry , it ’s entirely possible that you do n’t have a heart at all .
Denny Duquette Jr.
When asked about theirfavoriteGrey’spatients , almost everyone will reference Denny Duquette Jr. Jefferey Dean Morgan convey his undeniable charms to the part , once again raise the question of why every video show and movie seems determined to kill off the character that he plays . No matter how wrong viewers knew the Latinian language between Izzie and Denny was , it was impossible not to root for them .
Few moments in the series were as gut - wrench as Izzie showing up in a real promenade apparel only to discover that despite all her insane endeavour to save his life , Denny was go . As much as it hurt to watch his demise , most fans would ’ve preferred he stayed dead , rather than his strange season 5 return as a touch / delusion .
Derek Shepherd
Unequivocallythe love of Meredith Grey ’s life , there will never be another Der and Mer no matter how hardGrey ’s Anatomytries to create one . The romance between Meredith and Derek Shepherd ( Patrick Dempsey ) was one of the relationship that made the early seasons of the serial so compulsively watchable . Their will - they - or - won’t - they moral force had viewers hook from the start and introducing Derek ’s surprise spouse did footling to derail that faith .
As truly grievous as it was to watch Derek ’s last - which was basically the resultant role of medical incompetence - there really was no other way to write him out of the show and still remain true to the epic love story that Shonda Rhimes had been telling for over a decennium . McDreamy is still very much missed by both Meredith and fans .
NEXT : Grey ’s Anatomy : 13 Storylines That Hurt The Show ( And 12 That hold open It )