Grey’s Anatomy

For the past decade and a half ABC ’s aesculapian easy lay opera , Grey ’s Anatomy , has been one of the most successful and beloved shows on tv . And while the show made stars out of its cast of comparatively unknown actors , the staggering longevity of the series , in addition to its constant rotation of many guest stars , think that a lot of doer who had invitee spots onGrey ’s Anatomywhen they were still obscure have gone on to have some great success and recognition in the entertainment industry .

Undoubtedly , any work actor who has n’t gotten their big break yet would kill to have an visual aspect on a show likeGrey ’s Anatomy , and the fact that so many ofGA ’s former Edgar Guest principal have gone on to crowing and better things just goes to show how good of an eye they have for purge . So here are 10 of the most recognisable faces who had node roles onGrey ’s Anatomybefore making it big .

Dean Norris

Actor Dean Norris has really been work in television and film for quite a farsighted fourth dimension , his career began in the later 80 and he has been steadily working ever since . But this Yale - educated player really hit it big when he scored the role of Hank Schrader on the unbelievable telecasting seriesBreaking Bad . And while Norris begin act onBreaking Badin 2008 , he in reality had a guest appearance on two installment ofGrey ’s Anatomyin the twelvemonth 2007 . He play the role of Vince , a mechanic who was a part of the ferry crash and who was immobilise down by a trilled machine when he was helping other passengers run away .

Keke Palmer

Keke Palmer is yet another actress who has build up a really satisfying resume of guest spots on TV shows and bit parts in feature film motion-picture show before lastly hit it big . Keke ’s star seems to be continually on the rise , but her first really big break was probably when she nock the role of Zayday Williams on the abruptly - lived Ryan Murphy seriesScream Queens . She has blend in on to have meaning roles in TV shows likeStar , Berlin Station , andScream : The TV Series , but she also made an appearance onGrey ’s Anatomya distich of years before she start to hit it cock-a-hoop .

Mae Whitman

Mae Whitman is an actress who is most recognisable for her role in the NBC seriesGood Girlsas well as her prima role in the teen comedyThe Duff , but she has been working in the entertainment industry since she was literally a child .

By the meter that Mae made her appearance onGrey ’s Anatomyshe had actually already been working in TV and film for more than a decade , however , she was n’t the household name that she is today . She appear in a two - episode arc as a character who was having dangerous spinal surgical process to deal her severe scoliosis .

Leslie Odom Jr.

When it comes to a sudden burst of success in the amusement industry , actor Leslie Odom Jr. had a middling strange meteorological rise . Odom was actually a knead actor in TV and movie , but the project that launch him into the national spotlight was a Broadway gambling of all things . By this item , everyone on earth has hear ofHamilton , and Odom ’s role in the unparalleled dramatic play made him a near home name . But before he was hitting it big in the most successful musical in decennary , Odom had a individual appearance on the hit showGrey ’s Anatomyin the 5th episode of time of year 5 .

Dylan Minnette

Dylan Minnette is most recognizable for his part as Clay Jensen in the hit Netflix TV series13 Reasons Why , but he was a comparatively successful child actor who systematically booked work for years before at long last making it to the big leagues in telecasting . Minnette appear in theGrey ’s Anatomyepisode titled " Haunt You Everyday " .

The episode was a Halloween holiday episode , and Minnette played the role of Ryan . Ryan is a little male child who ’s mother work in the cafeteria and who also happens to need some ear reconstruction operating theater , and after " trick or treating " for everything the surgery requires he finally find what he was looking for .

Jesse Plemons

Jesse Plemons has reached the gamy bloom of his career ( so far anyway ) comparatively recently with the success of his appearance in TV shows likeFargoand films likeGame Night , but he first became a more recognized actor when he scored the gig of Landry Clarke on the TV seriesFriday Night Lights . And around the sentence that Jesse was first getting the testicle rolling onFriday Night Lights , he also made an appearance onGrey ’s Anatomy . Plemons was completely unrecognizable in the role though , he played the   part of a boy named Jake Burton who suffered from lionitis , which required Plemons ' face to be wholly covered by prosthetics .

Sarah Paulson

You do not need to mess with the Supreme . Sarah Paulson is most recognizable for her role in the horror anthology seriesAmerican Horror Story , but apparently she just has a certain do n’t mess with me vibe , because just prior to her debut inAHSPaulson come out as a unseasoned Ellis Grey in an episode ofGrey ’s Anatomy .

And if we may say so , that is some pretty brilliant casting . Paulson can well and pretty utterly encapsulate the intelligence , severity , and hostility that mostGrey ’s Anatomyfans and viewers would ask to see from the unseasoned medical sensation that is Ellis Grey .

Millie Bobby Brown

Before Millie Bobby Brown was throw van with her mind and mayhap single - handedly take down the USSR she made a   Edgar Guest coming into court on an episode ofGrey ’s Anatomy . The Stranger Things star had a client spot on the time of year 11 episode ofGrey ’s Anatomytitled " I Feel The Earth Move " , and she play a petty girl identify Ruby . Ruby finds herself in a cabin in the woods with her mum , and when a sudden earthquake hits Ruby ’s mama falls and injures herself . When Ruby call into the infirmary , Dr. Owen Hunt talks her through a series of treatment to help her mom before real aesculapian help can get .

Elisabeth Moss

Elisabeth Moss is a critically acclaimed actress who is most well sleep with for her role as June Osborne in the Hulu strike arrive at seriesThe Handmaid ’s Tale , but her star has been consistently on the rise since she began playing the role of Peggy Olson on AMC’sMad Men . And Moss in reality made a undivided episode appearance onGrey ’s Anatomyin the same year that she started onMad Men . Elisabeth represent a lineament named Nina Rogerson , the incredibly protective girl of a woman who was consistently sick because of a rarefied bone disease and who sadly died in surgery at Seattle Grace Hospital .

Tessa Thompson

When Tessa Thompson made her launching onGrey ’s Anatomyas Richard Webber ’s niece and a subsister of ovarian Crab , she was undeniably charming and cute as a button , but it ’s doubtful that anyone check her substantiate how much her career was going to take off in a few year . There are few use more sought out and covet in Hollywood than the function in the Marvel Cinematic Universe , and it seems that Tessa Thompson ’s persona in the MCU is only going to get bigger . Valkyrie was initially introduced into the MCU as one of Thor ’s many sidekicks , but she was of late advance to the King of Asgard .

NEXT : Grey ’s Anatomy : The Best Episode In Every Season , Ranked

Grey’s Anatomy Poster

Greys Guest STars

Scary Stories to Tell in the Dark Casts Dean Norris Header

Keke Palmer as Zayday Williams in Scream Queens

Retta, Christina Hendricks and Mae Whitman in Good Girls on NBC

Leslie Odom Jr in Hamilton the stage musical

Dylan Minnette in 13 Reasons Why Season 3

Jesse Plemons in Game Night

Sarah Paulson in Glass

Millie Bobby Brown in Stranger Things 3 Netflix

Offred stares at her former friend’s apartment in The Handmaid’s Tale Season 3 Hulu

Tessa Thompson Smiling

Grey’s Anatomy