Grey’s Anatomy

Medical dramaGrey ’s Anatomyhas been no unknown to plat twists over the last 16 years . Whether it be the surprise entry of Derek ’s estranged married woman at the end of season 1 or the aeroplane crash that left several doctors stagnant and injured in time of year 8,Grey’shas constantly shaken things up for shock value and to propel the plot line of the chief fibre forwards .

Some storylines have n’t been consummate surprisal , however . rooter have guessed going away from the show before they happened due to actors not renewing their contracts or being cast in other projects . Other times , guest stars do n’t make full-grown enough impact to stay on the show for an extended catamenia of time , making their exits less of a plot of land twist and more of an expected game machine .

Cristina & Burke’s Breakup

Cristina and Burke ’s kinship mirrored that of Derek and Meredith ’s ( where an intern and an attend to fall in making love ) . AlthoughMeredith and Derek were far from the stark couple onGrey ’s Anatomyas their job were plain   from the start , lover soon learned that Cristina and Burke were n’t either as their issues had a way of life of slowly reveal themselves .

When Burke declare oneself to Cristina and she had a hard time saying yes , or even picturing herself wear thin a ring , fans knew the relationship was doom . They continued conk ahead with contrive their nuptials , but it was a surprisal to no one when Burke realized that he could n’t marry someone who did n’t want to marry him . It was a heartbreaking time of year closing curtain , sure enough , but also a plot tress that watcher could see from a mile away .

Addison’s Exit From Seattle Grace

Addison Montgomery ’s reaching at the close of time of year 1 was a stark shock . When she announce that she was Derek ’s married woman and that Meredith must be the adult female sleep with her husband , rooter ' jaw dropped to the solid ground . It was the perfect way to terminate the first time of year and set up her eccentric electric arc going forward .

However , it did n’t storm anyone when she decide to leave Seattle Grace and initiate a new life for herself . She could only stay ferment at a infirmary with her ex - husband , his young girlfriend , and her ex - fan for so long before matter would get old . Plus , she was such a active , fascinating character that it was only right that she would get her own spinoff inPrivate Practice .

Mark Sloan’s Daughter Leaves

Nobody foresaw Mark Sloan getting a sojourn from his secret , pregnant teenage girl , Sloan Riley , during season 6 , but fan could narrate that her stay was only going to be temporary .

Sloan ’s fictional character was used as a patch twist to break up the otherwise goodly relationship between Mark and Lexie , creating stress between them as Mark grew nigher to his girl and her unborn shaver . Once the sister arrived , it was only a matter of time before Sloan decided to split , leaving her father heartbroken .

Callie Surviving The Tragic Car Wreck

When Callie Torres and Arizona Robbins got into a fearful car accident in season 7 that result in the infamous musical installment , fans were n’t trusted what to expect . Callie had just found out she was pregnant installment prior , and she and Arizona had only recently resumed their amatory relationship following Arizona ’s riposte from Africa .

ThoughGrey’shas had no problem belt down off main character in the past tense , it did seem improbable that they would stamp out both Callie and her unborn child , especially after impart Sara Ramirez an total sequence   to showcase their musical natural endowment .   When Callie survived and baby Sofia was born at the end of the episode , rooter were relieved more than shocked .

Henry’s Death After Marrying Teddy

For most of her first few seasons , Teddy Altman was used as the third point in the love triangle between herself , Owen Hunt , and Cristina Yang . She was n’t give any actual storylines of her own until Henry Burton was introduced as one of her patients in season 7 .

Due to his lack of medical insurance , Teddy made the decision to marry him so that he could get the care he demand . This resulted in the two of them actually falling in love , though happiness between a principal character and a node star onGrey’sis commonly short - lived . This is whyHenry ’s death inGrey ’s Anatomyeighth season was one of the most heartbreaking , yet predictable , exit way for Teddy ’s eccentric to keep to grow .

Mark’s Dying Post-Plane Crash

The plane clangoring in the time of year 8 finale had viewers on the bound of their seats , wondering which beloved doc was going to expire from their injuries . Within the first half - hour , it was revealed to be Chyler Leigh ’s Lexie Grey that did n’t make it , being eat up underneath the back half of the plane the group traveled in .

After an emotional goodbye and confession of on-key sexual love , Mark Sloan practically give up on surviving , need to be reunited with the sexual love of his life . Arizona assure that he made it back to Seattle alive , but in the first episode of time of year 9 , he succumbed to his injuries in the infirmary . His death was sad and tragic , but not a complete surprisal , give that there was no way of life Mark could ’ve gone on without his Lexie .

Owen & Teddy’s Inevitable Relationship

It was demonstrate from Teddy ’s introduction on the show that she and Owen Hunt had a history of thick friendly relationship and unrequited dearest . Despite always seeming to miss one another and messing up the timing of things , the two were always in a ' will - they - won’t - they ' wild-eyed situation .

That ’s why it was a shock to no one when Teddy and Owen finally got together   and even had the baby . His anterior marriages failed due to require different thing than his pardner , but with Teddy , they seemed to deal similar musical theme for the future . Although they aren’tone ofGrey ’s Anatomy’sbest duo , it does make common sense to keep them together .

Alex’s Exit And Divorce From Jo

Justin Chambers played Alex Karev for 16 seasons onGrey ’s Anatomy , and his release from the show was cover before his final episode aired . This gave fans a heads up about Alex ’s exit fromGrey ’s Anatomyand set aside them time to theorize about all the ways his character could bid leave-taking .

One of the most obvious choices was that he would be leaving his married woman Jo Wilson since Camilla Luddington had renewed her declaration for another time of year . Although manyGrey ’s Anatomyfans come up with some slap-up plot line for Alex ’s departure , the pediatric surgeon ended up leaving Jo for his ex - wife Izzie - which many fans had predict could happen .

Derek’s Death

Even though Patrick Dempsey hadsigned on for time of year 11 and 12 ofGrey ’s Anatomyin 2014 , his character , Derek Shepherd , died toward the end of the show ’s 11th season .

While it was a twist that changed the track of the serial , it was n’t a accomplished blow to fans as Derek was n’t as involve in that time of year ’s storyline as he had been before and Meredith was get a luck more independent storyline . In a way , it was like the writer were preparing fans for a Derek - less show , which is why fan were not surprised when his on - screen death occurred .

NEXT:5 Old Characters From Grey ’s Anatomy We Want To See retort In Season 18 ( & 5 We Do n’t )

Grey’s Anatomy Poster

A split image of Derek and Meredith hugging, Jo crying and Mark looking serious in Grey’s Anatomy

Burke leaving Cristina at the altar in Grey’s Anatomy

Kate Walsh as Addison standing in the hospital hallway in Grey’s Anatomy

Sloan holding her baby after giving birth in Grey’s Anatomy

Callie Torres and Arizona after the car accident in Grey’s Anatomy

Teddy and Henry looking at each other in Grey’s Anatomy

Owen and Teddy welcome their daughter in Grey’s Anatomy

Jo reads Alex’s divorce letter in Grey’s Anatomy

An image of Derek standing on the highway in Grey’s Anatomy