Grey’s Anatomy
Grey ’s Anatomyfeatures impossibly quotable dialogue , loveable fiber and insane aesculapian display case all set to amazing soundtrack . It also reminded an entire generation that ‘ 80s heartthrob Patrick Dempsey was still incredibly dreamy . The long - running serial publication has great deal of romances , both undeniably epic and utterly forgettable . gravely , few appearance shed their characters together with quite as much abandon asGrey ’s Anatomy . It ’s often fun to find out , but sometimes the event are cringe - worthy as well .
For every relationship that made viewers conk , there was another that had them looking for an apology to leave the elbow room . We all loveGrey ’s , so let ’s take an true look at the show ’s well and unsound couples .
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11. Best - Nico And Schmitt
Nico Kim and Levi “ Glasses ” Schmitt are the newest distich on this list , having just debuted in the show ’s current time of year . Grey ’s Anatomyhas long been one of the most reform-minded shows on tv set , but funnily , this is the first dear account to unfold between two male doctor at Grey Sloan Memorial . That ’s not why they make the cut here though . It ’s because Nico and Schmitt are adorable and the interpersonal chemistry between Alex Landi and Jake Borelli is undeniable .
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At first , Nico was unwilling to give Levi a chance on report of the doc ’s previous deficiency of experience with human . However , after an impassioned speech from Levi , Nico see the mistake of his ways and they are now formally a couplet .
10. Worst - Jackson And Maggie
It ’s unclear why it ’s so authoritative toGrey’sto make Jackson Avery and Maggie Pierce work as a couple , but they just do n’t . For one matter , Jesse Williams and Kelly McCreary have zero chemical science . For another , their Romance language is painfully dull . So , no sparkage combine with a major want of play makes for a boring couple that no one is rooting for .
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Maggie and Jackson are both awful characters in their own right and honestly , they deserve so much effective than being stuck in this relationship . Here ’s to hope that sports fan wo n’t have to stand through their romance for too much longer .
9. Best - Cristina and Burke
Cristina Yang and Preston Burke were one of several couples that made those early seasons ofGrey’sso obsessively watchable . While it is true that this relationship has been over for quite some time , Cristina ’s more late and longer love story with Owen simply ca n’t liken . These two truly understood each other . Plus , Sandra Oh and Isaiah Washington really clicked onscreen .
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From Burke spooning Cristina after her ectopic pregnancy to Cristina urgently try on to hide Burke ’s tremor , their relationship was full of ups and downs and aboveboard , it was kind of always doom to break down . However , that visual of them trip the light fantastic together in the kitchen is one that most viewers will always remember .
8. Worst - Owen and Amelia
Owen Hunt and Cristina Yang may not have been the majuscule mates , but they were a agency better lucifer than Owen and Amelia Shepherd . The relationship between these two was just a slew - or , a plane crash , as Owen called it - from beginning to finish . Most fans were grateful when they called it quits . Even blame the worst aspect of their romanticism on Amelia ’s brain tumor could n’t salvage this one .
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Viewers think that they ’d envision the last of this sorry conjugation , but the two found their elbow room back to one another eventually . They recently broke up again , hopefully this time for good . Seriously cat , we just want you to be felicitous .
7. Best - Izzie and Denny
The tragic love affair between Doctor Izzie Stevens and heart patient Denny Duquette Jr. was another kinship that made season 2 one of the show ’s good . Viewers knew that this love story was never going to have a well-chosen ending , but that did n’t hold back anyone from hoping that it would . There have been plenty of iconicGrey’smoments that had devotee reaching for the cheeseparing box seat of tissue , but few have been quite so intestine - wrenching as Izzie showing up in a literal promenade dress and recover Denny already dead .
The chemistry between Katherine Heigl and Jeffrey Dean Morgan was palpable andviewers fell for Dennyright along with Izzie . However , the less said about his season 5 return as a specter / hallucination , the better .
6. Worst - Alex and Ava
After swooning over the doctor / patient romance between Izzie and Denny , the one between Alex Karev and Jane Doe / Rebecca / Ava was a Brobdingnagian disappointment . Part of the event was the staggering lack of chemistry between Justin Chambers and Elizabeth Reaser , but the larger problem was that this storyline simply dragged on for far too long .
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Ava ’s individuality crisis raised some interesting questions , but the show was too focused on her lackluster human relationship with Alex to adequately research any of them . She kept leaving and every meter she reappear , lover cared a little flake less that she was there .
5. Best - Callie and Arizona
The love story between Callie Torres and Arizona Robbins was n’t just the first major kinship between a same gender couple onGrey ’s Anatomy , but it was one of the show ’s longsighted as well . After Callie ’s miserable marriage to George and her completely sparkless crack with Erica Hahn , it was awesome to see the orthopedic surgeon ascertain someone who was in reality veracious for her .
It is straight that things were never okay for these two after the airplane clangour , but they still stay one of the most compelling couples onGrey ’s . There ’s a reason why they live happily after -even if their reunion had to chance offscreen .
4. Worst - Callie and Penny
Callie and Penny Blake were basically the anti - Calzona : utterly no interpersonal chemistry , ludicrous and twelve shades of bland . You might say that the worst thing about Penny was that she did n’t struggle hard enough to get Derek the aesculapian care that would ’ve saved his lifespan . However , then you would be block about the fact that she hung around for way too long and ruin one ofGrey’sbest characters : Calliope Iphegenia Torres .
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Honestly , the Callie that we all know and love would not have uprooted her integral biography , and dragged her daughter and former partner through a brutal custody engagement , all for someone that she scantily knew .
3. Best - Jackson and April
Aside from the fact that there was some major heat between these two , Jackson Avery and April Kepner just made sense . April was kind of a divisive character for the first few seasons that she was in the serial publication . However , her relationship with Jackson really showed her in a different luminousness , add some more profundity in the process .
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Jackson and April are doubtless one ofGrey ’s Anatomy ’s most memorable couples and their goal was particularly grievous . Many devotee are still crushed that they never discover their way back to one another . Sure , the writer terminate up reunite April with the guy that she left at the Lord’s table , which is dainty and all , but seriously , Japril for life .
2. Worst - George and Izzie
The relationship between George O’Malley and Izzie Stevens is wide consideredthe greatest romanticist misstepinGrey’shistory . These two had developed an awesome friendship over the years and frankly , it undermined the intelligence of the hearing to arrogate that we ’d postulate them to scent up in bed together .
Making subject worse was the fact that Katherine Heigl and T.R. Knight had spate of interpersonal chemistry , at least until they started making out . At that point , watching them together candidly mat up kind of icky , as the two had become more akin to siblings than anything else .
