Grey’s Anatomy

During the fifteen yr , Grey ’s Anatomyhas been on the air , the bump off medical drama has been no stranger to controversy . This is primarily due to the major relationships that have been such a bragging part of the show . Throughout the year , Grey’shas caused infinite uprisings in its fanbase due to pushing relationships no one actually desire to see .

On the other hand , Grey ’s Anatomyhas also cater several of the most darling , well - known couple on television . What would television receiver romances be without iconic couples such as Meredith and Derek , or Arizona and Callie ?

Grey ’s Anatomyhas certainly given devotee a lot of love affair over the years , and that ’s mainly why it ’s been so successful . rent ’s take a look at a few major mates that the consultation bed , and a few that they detest .

Grey’s Anatomy Poster

10. JACKSON AND APRIL - BEHIND

" Japril " as it was fondly dub by lover , was a prominent success with the audience . The chemistry that Sarah Drew and Jesse Williams had was undeniable , and many moment shared between the span were exceptionally well - written . Jackson and April unquestionably had a quality about them that made people come down hard and dissipated for their love affair .

Before Jackson interrupted April ’s wedding , before they got espouse , before they had Harriet , Jackson and April were close friends . After some unforeseen events , they were the only two doctors left from the Mercy West merger . This brought them nigher and strengthened their adherence , and is presumably a self-aggrandizing reason as to why they were so loved .

9. JACKSON AND MAGGIE - REJECTED

perverse to Jackson and April , Jackson and Maggie had no chemistry whatsoever - none that made their love affair credible anyway . The generally negative reaction to the pairing of Jackson and Maggie was fuelled by the fact that Jackson and April were recently divide and had a unseasoned daughter together .

After all the drama that had result between a fan favorite , Grey’swasted no clock time throw Jackson into another relationship without apply the hearing any time to mourn , and that was a big error .

8. MEREDITH AND DEREK - BEHIND

After much drama and heartache , Meredith and Derek finally tied the grayback via a precious military post - it Federal Reserve note marriage in time of year 5 . Their jury-rigged marriage did n’t guarantee a happily ever after , though ; their kinship hit turbulence in later time of year , pass up to Derek ’s ultimate death in time of year 11 .

Fans still love this iconic dyad though . As far as the bulk of the audience is concerned , Grey’swill never produce a best duo . Meredith and Derek hold a special position in many viewers ' hearts , especially those who have been watching from the beginning .

7. MEREDITH AND FINN - REJECTED

After Izzie adopted a click in her post - Alex misery , she , Meredith , and George band together to leaven the loveable Doc . The dog seemed to be in good wellness at first , but due to out of the blue circumstances , Meredith ended up having to take several trips to the veterinary .

The veterinary who attempted to treat Doc for what was later reveal to be strong-growing cancer was Finn , and he quickly became Meredith ’s dash love interest . The two had the chemistry , for certain , but since the majority of the audience would not give up on the iconic " MerDer " pairing , Meredith ’s relationship with Finn end before it even started .

6. MARK AND LEXIE - BEHIND

McSteamy and McDreamy were two of the most beloved characters ever to be create onGrey ’s Anatomy , and both of their ultimate relationships were just as well - loved . Much like many rooter viewed Meredith and Derek as soulmates , the same title was used for Mark and Lexie .

This is a love story that ended up being probably the most tragic inGrey ’s Anatomyhistory , but to this day , fans still do it and lack this match affectionately .

5. OWEN AND AMELIA - REJECTED

Owen has had a big track record when it comes to his romantic relationship , and Amelia is no different , so the fact that these two were nothing but forged and detrimental for each other is no surprisal . After feeling the results of Cristina ’s departure and the loss of the on-going drama that stemmed from her complicated relationship with Owen , Grey’swriters became do-or-die and thus , the dynamic between Owen and Amelia .

This relationship was similar to the infamous Owen and Cristina bond certificate , but way worse . Owen and Amelia start off cherubic but became problematic in no time at all . Despite rebound from lover over this distasteful relationship , Grey’sshows no signs of giving it up just yet .

4. CRISTINA AND BURKE - BEHIND

Cristina was no alien to a disruptive relationship , and though her ordeal with Owen Hunt is plausibly the most ill-famed , Cristina was severely put through the wringer when it come to her whirlwind romance with Preston Burke .

Not only was Burke prone to mood swings and selfish behavior , but he vacate Cristina at the communion table on their wedding day and show no remorse for it when they reunite years later on . Nevertheless , Isaiah Washington and Sandra Oh had the chemistry that made fans root for their character ' Romance language .

3. RICHARD AND CATHERINE - REJECTED

Richard ’s earlier type arcs primarily revolved around his unfaithfulness . His affair with Ellis Grey was one of his absolute worst second , and the way he treat Adele during that clip was unforgivable .

ButGrey’sgave Richard a opportunity to redeem himself and his wedding , and a while things were good between him and Adele . But then Catherine come into the depiction , and although Adele had fallen ill with Alzheimer ’s , Richard moving on so tight felt improper .

2. CALLIE AND ARIZONA - BEHIND

Being the first primary LGBTQ+ couple on the show , Callie and Arizona will always be iconic . The two hold a special position in fans ' essence today , despite both reference having been written out of the show . There were very few fans that did n’t take root for Callie and Arizona from the beginning .

The couplet ’s relationship was put through some rough waters and finally , Callie and Arizona did not get the happy conclusion that they deserve . But that does n’t disregard the fact that they were groundbreaking , and citizenry are still talking about them today .

1. ALEX AND JO - REJECTED

Izzie and Alex ended their romanticism in the sixth season ofGrey ’s Anatomy , but they are still one of the show ’s most talked - about couples to this day , and there ’s a reason for that . The writers seemed to underestimate the winner of this relationship and the fact that so many hoi polloi absolutely loved it .

After notable recoil following Katherine Heigl ’s exit from the series , theGrey’swriters did the correct thing and waited a few time of year before introducing another major sexual love interest for Alex . The love story with Jo was also developed quite tastily and realistically , but none of the change the fact that fans just bang Alex and Izzie more .

NEXT : Grey ’s Anatomy : 10 Storylines that Have Aged Poorly

Derek flatters Meredith during her intern year in Grey’s Anatomy

Jackson and April kiss in Grey’s Anatomy

Maggie and Jackson standing together on Grey’s Anatomy

Derek embracing Meredith from behind

Meredith Grey and her dog Grey’s Anatomy

Grey’s Anatomy Mark and Lexie

Caterina Scorsone and Kevin McKidd as Amelia Shepherd and Owen Hunt in Grey’s Anatomy

Cristina confronts Burke at a wedding in Grey’s Anatomy.

Catherine Avery on Grey’s Anatomy

Callie and Arizona from Grey’s Anatomy

Jo and Alex from Grey’s Anatomy

Grey’s Anatomy