Grey’s Anatomy

The main cast ofGrey ’s Anatomyis absolutely monolithic , and has really built itself up over the year . The first couple of season were focus in the first place on the original houseman : Meredith , Cristina , George , Alex and Izzie , but as the show get on , more characters got their own fortune to shine .

However , becauseGrey’shas been on air for so long , it ’s rude that most of dramatis personae finally move on . When that happens , sometimes their character get a really awesome send off . regrettably , not all of the form are that favourable , and there have been some reasonably questionable exits from the series as well .

BEST: Cristina Yang

For the first ten time of year ofGrey ’s Anatomy , Cristina Yangbasically served as the co - lead character alongside Meredith Grey . These two budding sawbones were incredibly close and they were more than just best friends : they were the misrepresented sister .

Due to the importance of the character to the series overall , Cristina was given a retentive and absolutely executed storyline , in which she was nominated for the Harper Avery Award , and left Grey Sloan Memorial to run her own department in Switzerland . Her farewell episode is involve by fans as one of the show ’s most emotionally comforting .

WORST: Shane Ross

Although Stephanie Edwards and Jo Wilson change by reversal out alright , the third group of interne to grace the mansion ofGrey ’s Anatomywere not that appealing to viewers . Shane Ross first appeared in Season 9 , where he really appear to be quite likeable .

shortly , though , his character take a drastic uracil - turn in the following time of year after he caused a fellow intern ’s death . He became glum , bounderish and take , and no one really like him . His release was equally eldritch , as he decided at the last second to go with Cristina to Switzerland .

BEST: Derek Shepherd

Many buff might differ with this debut , but the fact is that Derek ’s exit from the show was a lot estimable than many of the other character . By the clip Season 11 came around , Derek was a pivotal part of the series , as he was married to the lead character .

Derek andMeredithhad two child by this point , and so to have Derek walk away from all that would just have been wrong . The only right mode to write out Derek was to kill him , and the producers made his expiry about as heartrending as they could get .

WORST: Callie Torres

Callie Torres was a bit of a funny character , as she was quite annoying in her first duo of season . Things turn around when she began to come out , and she gain a lot more confidence and rapidly became one of the safe characters onGrey ’s Anatomy .

However , a bit of her lineament growth was later on undone in her final season on the show . In Season 12 , Callie dated one of the doctors who killed Derek , and then forced everyone to go through a very afflictive custody battle just so she could take Sofia to New York .

BEST: Arizona Robbins

Arizona Robbins was one ofGrey ’s Anatomy ’s perkiest character , so it made perfect signified that she got her felicitous end . For the longest meter , Arizona was one half of the power couple bang as Calzona . However , the couple got dissociate in Season 11 .

Despite their divorcement , Arizona and Callie both stay friend , and they also shared a daughter together , Sofia . In Season 14 , though , Sofia began to pretermit her other mammy and started do up , so Arizona moved to New York to be nigher toCallie(apparently in more mode than one ) .

WORST: Izzie Stevens

Izzie Stevens was one an original medical intern on the show , so the fact that her departure was so underwhelming was just really disappointing . Before her going , Izzie had been part of one ofGrey ’s Anatomy ’s biggest plot line : her sexual love affair with Denny Duquette .

Izzie then got diagnosed with life sentence jeopardise cancer in the show ’s 5th season . She fight with everything she had and eventually beat the odds in Season 6 , only to leave the show a few episode later because she felt as though she did n’t belong in Seattle any longer . She would return in one of the show ’s most outrageous and controversial turn ( more on that afterwards ) .

BEST: Mark Sloan & Lexie Grey

Although these two are freestanding characters , they have been often paired together because they pass on the show in the same , tragic way . Markand Lexie grew to be two of the most loved characters on the series , and their relationship was to pass away for .

lamentably , they were very much two star topology - crossed lovers , for they were both victims of the plane clangour that hap in the Season 8 finale . Lexiedied on the vista , and Mark slip into a comatoseness soon after . Before they die , they both declare their passion for each other .

WORST: Erica Hahn

To be honest , Erica Hahn was not a very pleasant person . She was extraordinarily arrogant , and highly private-enterprise , specially with Preston Burke . When she joined the show as a serial even , her discourse of Cristina was absolutely lamentable .

Hahn ’s only real redeeming feature was her relationship with Callie , but even that turn dour when she exclaimed that it was n’t possible for Callie to wish both men and women . With that blazing bi - phobic comment , Hahn walked away , never to be seen again .

BEST: Stephanie Edwards

Stephanie was probably the best character out of her mass of houseman . Although   she could be a little irritating , she more than made up for it with her sass and her undeniable operative skills . Plus , she was a literal friend to Jo .

Stephanie ’s outlet was also belike the most striking passing in the whole ofGrey ’s Anatomy , as the entire Season 13finalewas focused on her and her attempt to keep a little girl from a monumental fire raging through the hospital . It was a truly howling episode .

WORST: Alex Karev

Alex Karev ’s exit was extremely controversial , and his going left theGrey ’s Anatomyfandom entirely part . Alexhad been a beloved mainstay of the serial for over fifteen seasons , until he made his last visual aspect in episode 8 of Season 16 .

Fans in reality did n’t know that this was to be his last sequence at the time , and his farewell instalment that came later on in the season tender an almost unlikely result : Alex abandoned his have a go at it wife to go be with Izzie , who had pass on him class before and has n’t been heard of in the series for the farseeing fourth dimension .   Additionally , he and Izzie actually had two children together .

NEXT : Grey ’s build : 5 Times Alex Karev Was An Overrated Character ( & 5 He Was Underrated )

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Sandra Oh as Cristina Yang in Grey’s Anatomy.

Gaius Charles as Shane Ross and Tessa Ferrer as Leah Murphy in Grey’s Anatomy

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Callie smiling on Grey’s Anatomy

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Katherine Heigl as Dr. Izzie Stevens in Grey’s Anatomy

Eric Dane and Chyler Leigh as Mark Sloan and Lexie Grey in Greys Anatomy

Brooke Smith as Hahn in the hospital in Grey’s Anatomy

Stephanie being treated for burns after traumatic fire

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Grey’s Anatomy