Grey’s Anatomy

Grey ’s Anatomyis change as Meredith Grey ( Ellen Pompeo ) will have a small role as the interim Chief of Surgery in season 19 ( perEntertainment Weekly ) . The newest season is shifting gears to introduce unexampled interns into Grey Sloan Memorial Hospital . The infirmary as see its fair share of characters ranging from Dr. to patient , but the relationships between characters drives the story .

Some of the good relationship of the drama are n’t the romantic ones , but the transmitted relationships and Grey Sloan is no stranger to get siblings work together . Whether colligate by bloodline , through marriage , or by choice , these sibling duette are fan favorites .

Heidi & Haylee Peterson

Heidi and Haylee Peterson , played by Holly Marie Combs and Alyssa Milano severally , only look in one episode , but it left a fall guy for viewing audience who are also fans ofCharmed . The duet appears as Sister once more in season 16 , episode 3 when their sister , Heather , precipitate into a construction site and is declare brain - all in .

relate : The 10 Best Patients On Grey ’s Anatomy , harmonise To Reddit

Redditorminnesotagalwrites , “ It did walk out a nostalgic chord seeing them together . ” Combs and Milano may not have been play their magical character fromCharmed , but they did bring the lechatelierite to control sorry vibes in a case of misguided personal identity .

Grey’s Anatomy Poster

Andrew & Carina

Andrew and Carina have an interesting relationship . She lie to him about their mother dying because she did n’t want to intermit his heart until he arrived in Italy . As the older sibling , Carina stress to protect him , specially when ex - girlfriends are concerned , and was the first to observe him potentially have bipolar disorder .

Tequila - lathinks they ’re “ definitely the most realistic sibling duo . ” Carina was the only one to believe Andrew when he believed Opal was involve with human trafficking . She is his stable foundation who takes care of him and ensure he ’s taking his medication . Before his untimely dying , Andrew ’s relationship with Carina was perhaps the most important in his life .

Meredith & Amelia

Meredith and Amelia have a special family relationship . Though thing were bouldered from the beginning , Amelia grow closer to Meredith than to her own sisters , as show when Meredith stay by her side as she retrieve from her nous tumor and Amelia see over Meredith after their settle out .

Redditormooodymiaexplains their growth being interesting by “ watching them go from heated public debate and harsh word … to common margin , sharing vulnerability , and becoming as close they are now . ” Derek ’s death brought them closer , do Amelia aperfect prospect for Meredith ’s new “ mortal . ”Their relationship has its ups and down , but family is forever .

April & Her Sisters

As the second oldest of four sisters , April had the unfortunate nickname of “ Duckie ” growing up , thanks to her braces , acne , and glasses until she blossom out in college . Kimmie , Libby , and Alice only appear in season 10 , but they ’re memorable . They fawn over Jackson and razz April in truthful sibling fashion .

Related:8 " Fan Favorite " Characters Redditors Find Annoying After Rewatching Grey ’s form

RedditorFull - Surroundexplains , “ As annoying as they were , April ’s sisters are underrated . ” April was becoming successful and desire to be taken badly and not be reminded of her “ despicable duckling ” puerility every five bit . Their limelight from the audience when provoke as April ’s bridesmaids is a uproarious moment for their relationship .

Split image of Amelia Shepherd & Addison Montgomery and Meredith Grey & Cristina Yang sitting on the floor

Addison & Amelia

Addison and Amelia are former sisters - in - jurisprudence , but their bond continue strong , having known each other for yr . Amelia even keep Addison ’s matter with Mark Sloan a mystery because of her dedication to Addison over her chum . Baykahnexplains , “ For some reason addison and shepard just hit different . ”

There ’s a sisterlike beloved and protectiveness between the women that ’s present betweenGrey ’s AnatomyandPrivate Practice . Addison does n’t want to see Amelia backslide into drug , and they systematically stand one another in times of stress like when Amelia gives nativity to her “ unicorn baby . ” Addison and Amelia ’s sibling relationship is a beautiful depiction of in - law remaining near after divorcement .

Owen & Megan

None of Owen ’s coworkers knew he had a sister until Nathan Riggs seem . Prior to her disappearance , Owen and Megan were skinny sib as she did everything he did and looked up to her older brother . His perception of her change after he learns Nathan was not the first to shaft in their relationship .

Related:10 Reasons Fans Are Still Watching Grey ’s Anatomy , According To Reddit

FanAkashaRulesYouwrites , “ They have the sizable sibling relationship IMO . ” Owen is a normal , protective older brother adjudicate to look out for his younger sister . He wants what is best for her even if it causes engagement . Owen even admits Megan is a proficient person than him .

Heidi and Haylee Peterson on Grey’s Anatomy

Derek & His Sisters

Derek does n’t have the best relationship with his four sisters , Nancy , Kathleen , Liz , and Amelia . Though Kathleen is n’t involve with the show , Nancy dislike his conduct with Meredith as his medical intern . He struggles to ignore Amelia ’s story with drugs and begrudgingly accept service from Liz when he needs a giver nerve to fix his paw .

However , some fans notice the Shepherd ’s home dynamic relatable . Redditorthebballplayer10explains , “ I come from a prominent crime syndicate , and I can tie in to Derek not having the best kinship with class . ”Derek is an importantGrey ’s Anatomycharacterand the dynamic with his sis break how important his employment and friendly relationship are to him .

Maggie & Amelia

Maggie and Amelia are only related through Derek and Meredith ’s marriage , but they have a beautiful friendly relationship that ’s consanguine to siblings . Amelia support Maggie through her mother ’s malignant neoplastic disease treatment and Maggie is the first to touch on to Derek as the “ other Shepherd . ” They bond early on over their romantic life , and it only grow from there .

touch : The Best Character Development On Grey ’s Anatomy , allot To Reddit

Redditorotterpop1991writes , “ I palpate like with all of Amelia ’s struggle in the past , she ask someone who shows up for her consistently . ” Maggie is that rock-and-roll for her , especially as the first individual Amelia tells about her genius tumor . She is a constant basic in Amelia ’s life , giving her the backup she needs .

Andrew and Carina DeLuca on Grey’s Anatomy

Meredith & Cristina

They may not be roue congenator , but the “ Twisted Sisters ” stay on in the bosom ofGrey ’s Anatomyfans years after Cristina leaves Grey Sloan Memorial Hospital . Grey ’s Anatomyhas plenty of underrated friendship , but Meredith and Cristina ’s friendship is perfect . They have combat and always manage to forgive one another and trip the light fantastic toe it out .

Meredith and Cristina are wholeheartedly each other ’s “ person ” with Derek even being ineffective to get between the two women . Redditorpetalinereminisces of them “ having sleepovers in Derek ’s bed with Derek in it . ” They have no formal relation , but the Twisted Sisters pick out each other as syndicate .

Meredith & Lexie

Thanks to her strained relationship with their father , Meredith had no desire to get to know Lexie . When Lexie showed up at the hospital , Meredith straight off shun her and complained about her mere comportment . However , asthegurlearlnotes , “ She was just set out to get beneficial at being a sister ” to Lexie when the woodworking plane crash .

Meredith was capable to grow her relationship with her half - sister , even donate part of her liver to help save Thatcher because she did n’t require Lexie to be without her dada even if Meredith had no relationship with him . Their bond grew was able to change significantly before Lexie ’s death .

Next:9 Times Meredith Should Have pass away & Only Survived Because Of Plot Armor On Grey ’s chassis

An angry Meredith with Amelia in the bathrrom

Split image of April Kepner and her sisters on Grey’s Anatomy

Split image of Amelia Shepherd and Addison Montgomery

Kevin McKidd and Bridget Regan as Owen and Megan Hunt in Greys Anatomy

Split image of Derek, Liz, and Amelia Shepherd on Grey’s Anatomy

Maggie and Amelia inspecting a scan on Grey’s Anatomy

Meredith and Cristina

Lexie and Meredith standing together in the hospital on Grey’s Anatomy

Private Practice