Grey’s Anatomy

Grey ’s Anatomyis famous for all the heartbreak it delivers with each season , and its 16th season was no exception . Romantic relationships are a staple fiber of the aesculapian dramatic event and are a large part of why the show is still so successful after 15 years on the air .

Of naturally , for devotee of the show to be heartbroken after a couple split up , they must first love and ship the aforementioned human relationship . Grey’shas always had a brilliant habit of pairing together the most unbelievable of amatory partners and making them polish so brilliant that fans draw a blank why they should n’t really turn to start with .

Mark Sloan And Lexie Grey

These two characters made theirGrey ’s Anatomydebuts a season apart and they could not have been more unlike . The only similarity between them was that they did n’t go forth a great first impression ; Mark was a middle - aged playboy andLexie hit on Derek .

However , as the two maturate , they began to get on the same wavelength . Mark was no longer a human beings cyprian and was ready to settle down down with someone . Lexie had develop into her own and refused to roleplay the purpose of Meredith ’s minuscule sis any longer . Basically , they were double-dyed for each other .

Meredith Grey And Derek Shepherd

plain , anyone who has ever watched the show experience that Derek and Meredith were think of to be . However , when the show started , Derek was just Meredith ’s merriment , little one night stand , who she never mean to see ever again .

This was followed up by the revelation that Derek was actually Meredith ’s boss at her place of work , which made things clumsy for the latter . as luck would have it for everyone involved , though , Meredith and Derek went on to tie the knot and were very well-chosen together .

For the first half of Season 15 , Link was set up as a potential new lovemaking sake for Meredith ( as if she does n’t have enough of those already ) . He competed against Andrew DeLuca but eventually lost out .

Link was a variety and caring mortal , with a wicked sentience of sense of humor . He was also fair simple , in that he know what he wanted and did n’t overthink everything . fundamentally the complete opposite of Amelia . However , the two fall in erotic love disregardless , made quite an endearing twosome , and now even have a baby together .

Meredith Grey And Nathan Riggs

In Season 11 , tragedy struck for Meredith as her long time onscreen husband , Derek , died . Meredith expend a while endeavor to add up to terms with Derek ’s death , and she eventually returned to Grey Sloan Memorial Hospital at the end of the season .

In Season 12 , Meredith met Nathan Riggs , and sparks soon flew between the two . Really , it was a little other for Meredith to start date so presently after Derek ’s death , but if you ignore that fact , Meredith and Riggs in reality made quite a funny and cute duet .

Alex Karev And Jo Wilson

Ignoring the highly dumb way in which their relationship ended , Alex and Jo eventually found themselves in a loving and attached marriage ceremony . However , that was n’t always the casing , as their first few seasons together werefairly jolty .

Initially , it appeared as though the two fibre could n’t stand each other . Jo give off the air of an entitled little princess , constantly weep over every footling thing , whereas Alex slept around with every woman in Jo ’s intern twelvemonth , with the exception of Stephanie .

Izzie Stevens And Denny Duquette

It is a fundamental rule that doctorsshould not go out their patient . However , becauseGrey ’s Anatomydelights in urinate its viewers ugly yell every chance it gets , there have been many Dr. - affected role relationships over the course of study of 16 season .

The most well - have it away couple though has to be , without a doubt , Izzie and Denny . Their brash , innocent flirt when they first met was absolutely adorable and it blossomed into a beautiful and heartfelt relationship , which ended unbelievably tragically .

Cristina Yang And Preston Burke

Some fans may discord with this entry , but the fact is that when their relationship was on satisfying undercoat , Cristina and Burke really had a lot of fun with each other . It only reallyhit fierce patcheswhen outside force intervened , such as Burke getting shot .

Of course , in the end , Cristina changed too much of herself for Burke for their relationship to exploit out in the long term , and perhaps this was unspoiled . Cristina was exceedingly challenging , and used Burke for his talent , while the latter try on to form Cristina into his perfect fiancé .

Miranda Bailey And Eli Lloyd

After the harrowingevents of the Season 6 finale , Bailey found herself breaking up with her boyfriend , Ben Warren , because she had to focus on place herself back together . During this metre , Bailey was in a vulnerable perspective .

Then , along came Eli . He and Bailey should n’t have worked because Eli was everything Bailey was n’t . He was able to relax at work , and remain calm , whereas Bailey liked to shout and give oral communication until someone did what she wanted . They in reality congratulate each other very well .

April Kepner And Jackson Avery

Despite the fact that they were in the same year as each other , April and Jackson had very little in common . Indeed , during their first season on the aesculapian drama , they hardly interacted with each other , choosing their other fellow doctor or else .

However , when both Reed Adamson and Charles Percy were obliterate in the Season 6 finis , Jackson and April slow drifted towards each other . This eventually unfold into a beloved kinship that manyGrey’sfans simply could not get enough of .

Richard And Adele Webber

For the first nine seasons on the show , Richard and Adele ’s relationship went through a lot . Technically , these two should have been separated before the serial publication began , as it transpire that Adele knew about Richard ’s affair , but still decided to stay with him .

This was just one of the reason why Richard and Adele ’s human relationship make for the way it did . The two always witness their style back to each other , even after separate up on multiple occasion . Sadly , their human relationship ended in the most heartbreaking mode , when Adele died after contract Alzheimer ’s .

NEXT : Grey ’s material body : 5 time Alex Karev Was An Overrated Character ( & 5 He Was Underrated )

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Link and Amelia with their baby Scout in the hospital in Grey’s Anatomy

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Izzie cries while hugging Denny’s body in Grey’s Anatomy

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Grey’s Anatomy