Grey’s Anatomy

Once you take the air through the door of Grey Sloan Memorial Hospital , as a patient role or a Dr. , odds are , you ’re going to cease up in some form of relationship onGrey ’s Anatomy . It ’s inevitable . ( You ’re also likely to be very attractive , upping the probability of multiple relationships . )

The ABC medical drama has had numerous romance among its faculty and affected role over its 14 seasons ( so far ) .

commonly , relationship involving a doctor and a patient are the 1 that hurt the show . After all , they have near to zero chance of lasting , not to name the fact that they should n’t happen in the first place .

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Then there are the relationships that embark on with one of the theatrical role being traitorous . Those are rarely ace devotee are run to root for to last .

This is also true of relationships where the main quality do n’t like one of their acquaintance ' choose pardner . In at least one causa , no one liked someone because that person was detrimental to the way the hospital was incline .

Some relationships were n’t mean to last at all , but were rather necessary stepping stones to make one individual quick for another one subsequently on .

Meredith hugging Derek in Grey’s

A couplet relationships ended up saving the show because they meant part got the only happy ending they could upon their exits .

In at least one case , all it took was one sad , very tragic conversation to make all the dramatic play between a twosome moot . They became a couple you require to see get the happily ever after they stargaze of because you sleep with they could n’t .

Here are the11 Couples That HurtGrey ’s Anatomy(And 9 That Saved It ) .

George leaning his head on Izzie’s shoulder on Grey’s Anatomy

Hurt: Izzie and George

Remember when George was married to Callie ( and alive ) ? It was during that time that he and Izzie log Z’s together .

fornication pretty much guarantees a couple a spot on the hurt side of this list .

Even worse ? Remember when they decided that they were in love and George was going to tell Callie , but Izzie stopped him ?

Arizona and Lauren shake hands before getting intimate

Callie was her honcho at the fourth dimension , and she want George to hold off to allow everything work out .

She even said he could use their tenacious hours and suggest that she was having an occasion . When he ask how long he should wait , she said a month .

Then , they realized they were better as best friends … and that was it ?

Camilla Luddington and Justin Chambers as Jo Wilson and Alex Karev in Grey’s Anatomy

Hurt: Arizona and Lauren

Arizona cheated on Callie with Lauren after the women ’s grow attractor arrive to a head during a violent storm .

Though Arizona tried to put a halt to it , Lauren secern her she was earmark to lose control . That was what Arizona did .

Then , in the following sequence , Arizona told Callie . It came back to Callie gain the decision for Arizona to lose her leg . " You did n’t suffer anything,“she told Callie . " I did . "

Penny and Callie sitting at the dinner table in Meredith’s house on Grey’s Anatomy

Arizona and Lauren was n’t about either of them , not really . It was a strong-arm reflexion of how Arizona felt about Callie ’s decision after the plane crash .

That , combined with the unfaithfulness , mean they never fend a chance to be anything electropositive forGrey ’s Anatomy .

Saved: Jo and Alex

It took years , but Jo and Alex finally got married in the time of year 14 finis .

The the true about her abusive ex - husband could have easily made them a couple that wound the show .

However , Grey ’s Anatomy — and Alex — address that in the right room ( including usher how their meetingcouldhave gone down ) .

Miranda Bailey and Ben Warren dancing in Grey’s Anatomy

Alex became someone fan could see in a serious family relationship with Izzie their last try at being together .

However , it was with Jo that   alex became someone you could see being — and staying —   married to someone for the longsighted run .

Sure , he made mistakes along the way ( like beating up Andrew ) , but he acquire from them and was willing to take responsibility for what he did .

Caterina Scorsone and Kevin McKidd as Amelia Shepherd and Owen Hunt in Grey’s Anatomy

Hurt: Callie and Penny

Remember when Penny was creditworthy for Derek losing his life history ? The resolution is probably yes , because noGrey ’s Anatomyfan will forget that anytime shortly .

Then , Penny showed up as Callie ’s girlfriend — at a dinner at Meredith ’s house . To make thing bad , she announce she was go to be working at the infirmary . Did these two ever stand a opportunity ?

That was n’t even factor out in Callie ’s relationship with Arizona . While the two were broken up , fans wanted them to get back together . ( Arizona ’s way out suggest there was hope . )

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It was because of centime ’s determination to move to New York — and Callie ’s to go with her — there was the custody engagement for Sofia .

That did n’t even end up mattering , since Arizona then gave Callie plane ticket to New York and agree to joint custody .

Saved: Ben and Bailey

Does anyone else have a cushy smirch for kinship that last across display ? Ben may have act from medication to push fires onStation 19 , but it has n’t negatively affected his wedlock .

It ’s just something else the couple has to deal with , and so far , they ’ve do by it well .

receive Bailey with Ben has allowed the show to search a softer side of the doctor , one people were n’t used to seeing in earlier seasons .

Greys Anatomy Alex Rebecca

Not only are the two of them safe for and there for each other , it ’s always delightful to see them be a syndicate with Tuck .

They do n’t always have to check — on a professional or personal floor — but both show will be at their good with them ending up on the same page .

Hurt: Owen and Amelia

perhaps one of the bad role about Owen and Amelia is that they have electric potential — now .

Her brain tumour could explicate most of her strange behavior for years . Now that it ’s gone , maybe they could play things out — if they start afresh .

The problem with that is fans remember everything that pass off before .

Callie Torres and Arizona Robbins standing together in Meredith’s living room in Grey’s Anatomy

Owen and Amelia each had plenty of baggage going into their relationship , and even once they were together , thing were n’t much better .

She almost pull a Runaway Bride before their wedding , and he wanted kids , while she did n’t .

Then there ’s the fact that Teddy ’s back in the exposure ( and fraught ) . That place up a potential love triangle . Those are always tricky and have the potential to destroy a show .

Nathan visits Meredith to try and work things out

Saved: Mark and Lexie

Mark and Lexie may not have been the good couple at times , but they had potential . In fact , if they had n’t lost their lives in the plane collapse , it ’s possible they could ’ve been something great .

The on - again , off - again nature of their relationship — and Lexie ’s relationships during the off - again part — was n’t the best .

However , it was Lexie and Mark ’s goodbye as she was trapped under the plane that cemented them as a couple fans wanted to see get a glad ending .

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He tried to lift the carpenter’s plane off of her himself , something he realistically could never have done .

They were " imply to be " together , they said , even thinking about a life together . It ’s just too spoiled they never got to have that .

Hurt: Alex and Rebecca (aka Ava)

Let ’s be honorable . When one individual does n’t commend anything about their aliveness , a couple never really brook a chance . When one person is a patient and the other a doctor , that ’s dependable as well .

When Rebecca regained her memory , she lied at first because she ’d been in an unhappy marriage . Then , after she left , she return to Seattle to be with Alex .

That leave in him being suspended for hook her into the gallery to check a surgical procedure .

They did n’t meet under the best consideration — at the scene of an fortuity — nor did they have any real unfermented here and now .

Instead , their relationship began like it started : with Alex taking care of her . Rebecca had thought she was pregnant ( and did n’t believe she was n’t ) and prove to take her own life .

Saved: Callie and Arizona

Arizona and Callie ’s first buss was for certain memorable in the best fashion — and that ’s a sign of a in effect couple . " There will be people lining up for you,“Arizona assure her and barrack her up before kissing her .

They had their fair share of drama , but they got past it .

Callie slept with Mark , which lead to her being significant , but the three of them raised Sofia together .

Arizona cheated on Callie with Lauren , because she had n’t forgiven her for taking her branch after the airplane crash .

Even after that — and a hands battle for Sofia — there always seemed to be hope for the two of them . That was somethingGrey ’s Anatomydid well , so it was fulfill that Arizona ’s exit included texts with Callie and moving to New York , where her ex was .

Hurt: Meredith and Nathan

Meredith and Nathan had one affair in plebeian : they both lose the great unwashed they loved . She lost Derek , and he lost Megan .

However , he got his lost dear back .

All the steer cast onGrey ’s Anatomythat Megan could return have in mind Meredith and Nathan never stood a chance .

There was no way that the series was n’t give way to capitalise on her still being alive . She is , after all , also Owen ’s sister . There was too much story to tell there , as was seen once she appeared onscreen .

Some fans also just were n’t — and still are n’t — ready to see Meredith in another serious human relationship . The fact that what connected her and Nathan was she lost Derek made that even worsened .