Grey’s Anatomy

Few shows have lasted as retentive asGrey ’s Anatomyhas . The series just twine its fourteenth season on ABC and was renewed for a 15th . It has become a telly staple fiber and inspired a whole night of programming on the internet . Thanks toGrey ’s , Shonda Rhimes has created her own empire and fans are obsessed .

Since the show premiered in 2005,Grey’shas introduce fans to innumerous medical terms and truly teach the signification of bad luck .   The employees of Seattle Grace Hospital , now Grey Sloan Memorial , have endured deranged shooter , bombs and several transportation accidents ( there ’s been a plane smash , a train crash , a ferrying crash and more ) .

Each one is more devastating than the last , especially when it claim the life of a major character . It ’s hard not to fall in love with the characters ofGrey ’s Anatomy ; each one is unlike , but more often than not , bring unbelievable insights . But , it ’d be impossible to get bind to these characters if the actors that play them were n’t so cracking .

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Grey ’s has attract some badly high caliber player during its long run . On screen , their functioning are incredible . But off screen , some of them are n’t always the best . This list will countdown some of the truly tremendous personalities on the show , but may shatter some illusions on others .

Here are10 Grey ’s Anatomy Star Who Are Legitimately Sweethearts ( And 5 Who Are n’t ) .

Sweetheart: Sarah Drew

Since conjoin the show as April Kepner , Sarah Drew has been a standout . Fans directly connected to her , and Kepner ’s devotedness to her religion was a plot line not often seen on connection television . In the later time of year ofGrey ’s , Kepner ’s spark has focused on her crisis of faith . It ’s been dividing for sports fan , see her become cynical and reckless , with some fans arguing that she ’s become an irritating character . But , they still love the idea of April and Jackson being together . So seeing him with Maggie this time of year has bring out some of the meaner side of Twitter . At the same time , it ’s brought out the sweetness in Drew herself .

She recentlyTweeteda message to her fan , encourage them not to send hateful messages to Kelly McCreary ( who encounter Maggie ) . She write , " My beautiful , loving , truehearted sis , Kelly , is a brilliant , fiercely talented team role player who ALWAYS prove up and dedicates herself to the story she is demand to tell . " give that it was recently revealed that Drew was let go from the show , some might anticipate her to be bitter . Particularly because reviving the # Japril relationship could have been a way to keep her around . But , she ’s handled herself with nothing but grace and humbleness .

Sweetheart: Ellen Pompeo

Ellen Pompeo has been the heart ofGrey ’s Anatomyfrom the showtime , playing the show ’s namesake . Her character has always been a little dark and twisty , but in a good way . In real life , Pompeo is exchangeable in a lot of ways . She ’s a little grating around the edges and is n’t shy about using mature oral communication . She ’s from Boston after all . But at her nitty-gritty ,   Pompeo ’s a good one . When it was announced that both Sarah Drew and Jessica Capshaw would both be forget the show at the end of this season , some speculated that it might be because of Pompeo ’s significant contract . Earlier this twelvemonth , she ink a mountain to continue on the show for a reported $ 20 million .

Pompeo made it very clear that this was definitely not the cause , notice that she was even surprised when the intelligence intermit .

She was even classy enough to give them both love posts on Instagram . Pompeo thankedCapshaw , " for bring it the agency you have brought it for 10 amazing years … what a blessing you are and what a donation you made to video history . " Of Drew , Pompeo enjoin , " Your warmth and talent for storytelling has match so many hoi polloi chivy think and Greys is a better show because of it and you . " She ’s a family act , always encouraging women to bear other women . Pompeo ’s been very capable about her journey and her increased transparency after release her salary has only made her more admirable to fans .

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Not: Patrick Dempsey

Thanks to his time onGrey ’s , Patrick Dempsey may constantly be referred to as just " McDreamy " . He was the gorgeous , kind - hearted , albeit riotous medico that everyone want to be with . So , when he was very all of a sudden   written off in time of year 11 , fans were in serious denial about things . harmonise to reports , the brusqueness of thing was mostly because it was a one - sided thing . Dempsey wanted to leave , so they let him . But why could n’t he get a decent , open - ended exit like Sandra Oh rather than leave Meredith a widow woman ? Well , that ’s also because of Dempsey .

conceive his character ’s personality , it ’s comfortable to think ( and hope ) that Dempsey would be just as marvelous in substantial life . Unfortunately , that might not always be the causa . early on on in filming the show , Dempsey got in a heated altercation with co - champion Isaiah Washington and from there , it seems things only got worse . Ellen Pompeo lately noted inan interviewthat ,   " You only get [ written ]   off when your behavior is unfit . If you ’re a nice actor , you   [ go ] nice . " Well , Derek ’s   pass was jolly rough . Over the year , Dempsey ’s reputation for being a prima donna has only increase and he ’s evenadmittedthat he " can interpret " why people retrieve that about him .

Sweetheart: Jesse Williams

Since season six , Jesse Williams has played Jackson Avery , Mark Sloan ’s prodigy and low - key medical royal house ( his gramps invented the Harper Avery Award ) . His fictional character is make out to be a bit unregenerate , but ferociously loyal and determined to make thing happen the right agency . In real life , Williams is definitely just as truehearted . When the release of Jessica Capshaw and Sarah Drew was declare , he was among the show stars who write heartfelt messages to the women and fans . Williams made a head to refer how upsetting the news was for him personally . In his farewell message to the actresses , Williams not only highlighted their work on screen , but their personalities off screen as well .

He write in hisTweets , " Their immense talent speaks for itself but it ’s them as people that I ’m so grateful to be intimate , privileged to have worked with and learned from . " Off screen , Williams himself is incredibly outspoken about societal judge issues and his   inclination of   achievements in activism is astounding . Williams is the untested member of the board of directors at   The Advancement Project ,   the   executive producer   ofQuestion Bridge : Black Males , and in 2016 he   win the humanist awarding at the   2016 BET Awards .

Sweetheart: Camilla Luddington

liken to   some of the cast , Camilla Luddington is still relatively unexampled toGrey ’s Anatomy . She join the show as a fall back theatrical role in time of year nine , getting relegate up to series regular in season 10 . But , her fictional character Jo Wilson has become a vital slice of the show . She help Alex grow into an even more matured mortal and as of the time of year 14 stopping point , is officially his married woman . But more importantly , her abuse electric arc betimes in season 14 helped open up the conversation for woman everywhere . Luddington fully empathise the exercising weight of the story and was well-chosen to disgorge light on such an authoritative subject .

She ’s incredibly involved with her fans on Twitter , taking the time to live tweet when she could   and answer as many questions as possible . Luddington intelligibly has a sozzled shackle with her co - star Jessica Capshaw . The two exchange adorable messages online all the time . If there ’s any doubt left of just how wonderful Luddington is , it should be crystallize up by her loyalty to her other castmates . When one publication advise interview should sense sorry for Sarah Drew after her Cagney and Lacey reboot did n’t get picked up , Luddington stepped in . She tweet that or else of pity Drew , fans should keep that she actually has a new movie add up out soon .

Not: Katherine Heigl

WhenGrey ’s Anatomybegan , it follow five central characters , beginning their internship at Seattle Grace Hospital . Among those five was Izzy Stevens , play by Katherine Heigl . Her fictitious character was known for her empathy , as it was both her biggest metier and her fatal flaw . It ’s no secret that Heigl ’s release was a dramatic one . She was very heart-to-heart about the fact that she did n’t like the writing she was being yield for Izzy . She was so assailable in fact , that she take herself out of Emmy tilt because she did n’t consider the work merited the honour .

Thanks to the stories surrounding her departure , she became know as someone who is gruelling to exploit with .

Shonda Rhimes even used Heigl ’s name as a cosmopolitan term for describing difficult actors . During an audience about one of her other shows , Scandal , in 2014Rhimes notedthat it was a bang-up environment and that " there are no Heigls in this spot . " These twenty-four hours though , it seems she might ’ve turn thing around . During an show on Howard Stern ’s radio show in 2016 , Heigl admit that she handled things wrong . She add that she should ’ve just say herself to " Shut up , Katie . " After years of medium criticism , Heigl has work to get back into the world ’s right goodwill and start   her function onSuitsthis time of year .

Grey’s Anatomy Sarah Drew

GREY’S ANATOMY - ABC’s “Grey’s Anatomy” stars Jesse Williams as Dr. Jackson Avery. (ABC/Bob D’Amico)

Sweetheart: Justin Chambers

Out of the original five onGrey ’s Anatomy , Alex Karev was probably the most instantly unappealing . He was self-important , patronise and oftentimes , just by and large untimely . But , that start smirch is exactly what ’s made him so compelling through 14 seasons ofGrey ’s Anatomy . Fans have love Alex ’s phylogenesis from angry and unlovable to supportive friend .   When Christina left , he stepped up to become   Meredith Grey ’s person and has done a great job . He ’s teach from his mistakes and even found honey again . In the real world , Justin Chambers is even more lovable .

According to his castmates , Chambers skin the most with   the complicated line on the show , but it makes for hilarious bloopers . But on top of his temper , Chambers has a huge center , specially for his coworkers . He tends to lose rest when they ’re scramble , literally . Chambers suffers from a biologic eternal sleep disorder . As a result , there have been times where he ’s only slept for a individual time of day over an integral hebdomad . One of his high-risk bouts came in 2008 , as Chambers   was so worried about   the Grey ’s work party lose their jobs during the writer ’s strike – the show completely halted shooting – that he give the point where   he decided to seek professional handling .

Sweetheart: Sandra Oh

Meredith Grey can be difficult to care with at times . Particularly in the early seasons ofGrey ’s , she was in a very sullen place and did n’t confide in many people . The one soul she trusted above all else was , well , her mortal . Cristina Yang was just as black and twisty , if not more so . She was smart , work out and drive , along with being the perfect best friend for Meredith . Being one of the few remaining serial archetype ,   Sandra Oh ’s exit was hard for fans to accept , but , she handled it in the perfect way . The decision to leave was very common between Oh and the showrunners . grant to her on - screen BFF Pompeo , Oh was very clear on the fact that she only wanted to do 10 season . Pompeo even went so far as to say"they do n’t get much classier than Sandra Oh . "

Her eccentric of Christina Yang was mostly passably blunt and oftentimes rude .   In literal life , Sandra Oh is the opposite . She was nominated for , and won , several laurels during her time onGrey ’s , snagging Emmy noms after seasons one and two . Both times ,   Oh opted to take her parents to the honor show with her . More than being fun to work with , Oh is known for being implausibly humble . During an consultation onGeorge Stroumboulopoulos   Tonightin 2012 , she noted that she does n’t consider herself a famous person . She just focuses on being an artist and lay out well oeuvre .

Not: Melissa George

It ’s a fleck hard to conceive that before Christina , Meredith did n’t have any friends . She was dedicated to her job , but she was never straight-out antisocial . In time of year five , theGrey ’s Anatomyshowrunners decided to introduce Meredith ’s former well friend Sadie Harris , played by Melissa George . The character got pretty miscellaneous reactions from fans and critic alike , as a whole she was n’t the greatest person . She was characterized as reckless and someone who never really thought everything through . In her final installment , it was revealed that Sadie actually cheated her way into the residence program and she departed shortly thereafter , never becoming a serial regular .

Off screen , Melissa George has had some battle   In 2017 , she had aserious altercationwith her boyfriend which terminate in both of them being charged with assault . The sad part is that their shaver had to suffer through the court conflict as well . The courts ordered that George and her boyfriend have joint hands of their kids , mean neither one could take the kids out of the land without written license from the other . But , just a few days after the assault , George attempted to take her kids with her to the U.S. , leading to her facingkidnapping charge .

Sweetheart: Chyler Leigh

Before she was keeping the Earth dependable from other - world visitors onSupergirl , Chyler Leigh was solely saving the resident of Seattle . Lexie Grey rapidly became a fan - favorite character and her   passing was particularly grievous . She was one of the life claim by the infamousGrey’splane crash . It was especially rocky on fans because she and Mark had literally just made plans for the balance of their spirit . The decision to write off Lexie was reportedly a mutual one . At the starting line of time of year eight , showrunner Shonda Rhimes   allowed Leigh an extended hiatus so she could spend clip with her kinfolk .

Leigh he was mostly absent from the   first few episodes of the time of year and made her exit at the end of it to be with her   family .

In 2014 , two twelvemonth after her final sequence , Leigh let out that star onGrey’swas " not worth it . " , but she did n’t mean it with hostility . She clarify in the same statement that she loved every mo of her time on the show and it was only tough because she was missing out on her kids ' lives . She had nothing but kind words forGrey ’s Anatomyand even gave a nod to it in a late episode ofSupergirl . While administering a few mental testing for a friend , her character Alex note that before she joined the DEO , she want to be a MD and even had a gig lined up in Seattle .

Ellen Pompeo as Meredith Grey smiling on Grey’s Anatomy

Patrick Dempsey as Dr Derek Shepherd Greys Anatomy

JESSE WILLIAMS

GREY’S ANATOMY - ABC’s “Grey’s Anatomy” stars Jesse Williams as Dr. Jackson Avery. (ABC/Bob D’Amico)

An image of Camilla Luddington as Jo Wilson on Grey’s Anatomy

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Justin Chambers as Alex Karev on Grey’s Anatomy

Sandra Oh on Grey’s Anatomy.

Melissa George Greys Anatomy

Chyler Leigh as Alex Danvers in Supergirl

Grey’s Anatomy