Grey’s Anatomy

Not only are theGrey ’s Anatomywriters exceptionally talented in the intriguing style that they write the series ' primary characters , but they are also skilled at arrive at the patients and blow over invitee star very memorable .

An important aspect of the series are the patients . Save a smattering that welcome multiple instalment arcs , most patients come and go within one episode . make such a short period of clip to make these small-scale characters real and interesting enough so that the audience spring up to care about their taradiddle , is no easy task . But most of the time , Grey ’s Anatomyabsolutely nails it .

The serial publication also owe a notable amount of this succeeder to the casting department , as a strong character ask a strong actor . Grey’shas always had an amazing cast of characters , and the Edgar Albert Guest actors are no exception . get ’s search 10 of the serial publication ' good Edgar Guest stars .

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10. MANDY MOORE

Mandy Moore was a fitting choice to play the lovable Mary Portman . With her husband , Bill , Mary came to the hospital in season six , for a colostomy bag reversal surgery . She was Dr. Bailey ’s patient , and someone whom Bailey valued greatly .

Mary and Bailey ended up survive together during the hospital shooting . Bailey managed to get Mary out of that ordeal awake , but this made it all the more grievous when Mary derive back to the hospital to have her surgical process , and ultimately died . Bailey performed the procedure perfectly , but after the surgery , Mary simply did not wake up . This patently was devastating to Bailey . Mandy Moore ’s sweet character was a tragic release , but a beautiful portrayal .

9. JEFFREY DEAN MORGAN

Who could ever forget Denny Duquette ? Jeffrey Dean Morgan ’s portrayal of the charming patient role made this plot line one of the most well - live onGrey ’s Anatomy .

Denny was Dr. Burke ’s patient role and was ailing with congestive centre failure . Famously , Izzie Stevens , who happened to be an intern on the typeface , fell hard and fast for Denny . The two had a heartwarming but very short - lived romance before Denny died of a origin clot after a successful heart transplant .

Denny became probably the most famous guest star onGrey’s , and actually appear in a few seasons , even after his end . As a affected role , a imaginativeness in Meredith ’s purgatory , and as a ghost appearing to Izzie Stevens as a symptom of her brain tumour , Denny Duquette is utterly unforgettable .

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8. DORIS ROBERTS

well known for her role onEverybody Loves Raymondas the domineering but lovable Marie Barone , the late Doris Roberts showed up as a patient onGrey ’s Anatomyin time of year 7 . Roberts ' character was a wealthy but vitriolic woman named Gladys Pulcher , who had been diagnosed with lung cancer .

Gladys ' genus Cancer at last became last , and as she was pall in the hospital , she had no supporter or house come to visit her . This prompted Alex to get close to her , and in the end , he wound up convert her to donate her portion to his African orphan project . Doris Roberts ' appearance onGrey’swas short but very memorable .

7. SETH GREEN

role player , director , and co - creator of Adult Swim’sRobot Chicken , Seth Green ’s appearance onGrey ’s Anatomywas one of the most memorable .

His character was sweet and wizardly , Nick Hanscom , who add up to Seattle Grace for a tumour resection from Mark Sloan . The procedure was successful , however Mark was only capable to plow Nick ’s carotid artery with a slender fluttering of skin .

Lexie frequently checked in on and examined Nick , and the two became tight . One day , after an attempt to cheer Lexie up , Nick began laughing and his carotid arteria suddenly burst , hence setting off the unforgettable scene in which blood spray all over the room while Lexie desperately essay to save Nick .

Mary Portman lies in hospital bed in Grey’s Anatomy

6. TESSA THOMPSON

In season 2 , well - known actress , Tessa Thompson , portrayed Camille Travis , Dr. Webber ’s seventeen - twelvemonth - old niece . It ’s revealed that Camille antecedently had a struggle with ovarian cancer when she was fourteen , and this resulted in doctors hit one of her ovaries . But her other ovary was leave in hope of preserve fertility , and upon try Camille , Addison expose that the cancer has returned .

Addison inform Adele that Camille ’s prognosis is not good , and later , this storyline results in the hospital hosting a prom for Camille . Tessa Thompson ’s portrayal of Camille was one that lover will not presently forget .

5. KEKE PALMER

In season 10 , Cristina conducted a clinical tryout for hoi polloi with Hypoplastic Left Heart Syndrome ( HLHS ) . Keke Palmer - noted for her persona inAkeelah the Bee , Joyful Noise , andTrue Jackson , VP -portrays Sheryll Jeffries , a pregnant seventeen - class - one-time girl .

Sheryll was bright to get into Cristina ’s tryout , as she suffered from HLHS . However , Cristina turned her down , and Sheryll gave birth before long after in the same episode . While she had very few scenes , Keke Palmer makes the persona very memorable with her emotional , compelling performance .

4. JOHN CHO

John Cho has starred in severalStar Trekmovies , Harold and Kumar , and a coupleAmerican Piemovies . But one of his often overlooked roles was his one - instalment coming into court inGrey ’s Anatomy . In the series ' second season , John Cho portrayed Marshall Stone , a operative intern from Mercy West .

Marshall ’s level was a devastating one ; due to the debilitation that comes from being a operative intern , he shine asleep while drive and induce a severe car accident . In the destruction , the chance event tragically bolt down a pregnant woman . The scene where Marshall makes a tearful apologia to the woman ’s family is one that remains heavy to leave .

3. JURNEE SMOLLETT-BELL

Jurnee Smollett began her acting life history when she was a kid , come along on situation comedy such asOn Our OwnandCosby . InGrey ’s Anatomy ’s 4th season , she portrayed Beth Monroe , a young girl who had a malignant glioma .

The tumor had cause paralysis on her good side , and as chemo and radiation therapy was leaven to be unhelpful , Beth was selected to participate in Meredith and Derek ’s clinical trial run . She had been dating Jeremy West , a boy she met at Mayo Clinic when they were both encounter treatments for their tumours . Jeremy also participate in Derek ’s clinical trial , but the trial ’s only success was with Beth .

2. ABIGAIL BRESLIN

This famous child actress who had antecedently starred in moving picture such asLittle Miss SunshineandRaising Helen , had an interesting one - sequence role inGrey ’s Anatomy ’s third time of year .

Breslin ’s character , Megan Clover , seemed to sense no physical bother . presently it was revealed that she in fact feel no physical sensations of any kind , and Alex , Addison , and Bailey discover that Megan has Congenital Insensitivity to Pain with Anhidrosis ( CIPA ) . Even though this instalment aired way back in 2006 , Abigail Breslin ’s appearance is still an unforgettable one .

1. SARAH PAULSON

The forever iconic Ellis Grey was primarily limn by Kate Burton . But in the time of year six episode,“The Time Warp”,American Horror Storystar , Sarah Paulson , take on the captivate role .

The episode present a series of many different characters ' flashbacks , featuring instances such as hurtles Bailey had to face when she was an intern , a case Alex and Callie had to work , and most notably , Richard ’s story about the time he and Ellis attempted to deliver a valet de chambre who was ailing with AIDS .

Though Kate Burton is unarguably the ultimate Ellis Grey , Sarah Paulson ’s carrying out is an iconic one , and retch her was a perfect choice .

Denny Duquette in hospital bed smiling in Grey’s Anatomy

NEXT : Grey ’s Anatomy : All of Meredith ’s Romances , Ranked

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Nick Hanscom in Grey’s Anatomy

camille grey’s anatomy

keke palmer grey’s anatomy

john cho grey’s anatomy

Beth Monroe in Grey’s Anatomy

abigail breslin on grey’s anatomy

sarah paulson

Grey’s Anatomy